A case of diabetic ketoacidosis in a type 2 diabetic patient accompanied by Plummer's disease

Ai Murao, Masanori Iwase, Tan Tominaga, Hiroshi Ohtani, Hidefumi Tomari, Yasuhiro Idewaki, Masahiro Nakano, Hiroshi Jyouzaki, Udai Nakamura, Takanari Kitazono

研究成果: ジャーナルへの寄稿学術誌査読


A 51-year-old woman was admitted to our hospital due to nausea and upper abdominal pain. She had a consciousness disorder and tachycardia. Her laboratory data showed hyperglycemia (plasma glucose level: 694 mg/dl), ketosis (total blood ketone body level: 15.4 mmol/l) and acidemia with preserved insulin secretion and negative findings for anti-GAD antibodies. She was diagnosed with diabetic ketoacidosis, and insulin therapy was commenced. She had a nodular goiter in the left lobe of her thyroid (3×4 cm) in addition to hyperthyroidism (TSH <0.01 μ IU/l; Free T3 3.04 pg/ml). Thyroid autoantibodies were negative; however, 123I thyroid scintigraphy revealed a hot nodule corresponding to the tumor. Plummer disease was diagnosed and hemithyroidectomy was performed. After the surgery, the patient's glycemic control was excellent and the insulin therapy was withdrawn. It is well known that the development of diabetic ketoacidosis may be accelerated by hyperthyroidism mostly caused by Basedow's disease. Clinicians should be aware of Plummer disease as a cause of hyperthyroidism during episodes of diabetic ketoacidosis in patients with type 2 diabetes mellitus.

ジャーナルJournal of the Japan Diabetes Society
出版ステータス出版済み - 2015

!!!All Science Journal Classification (ASJC) codes

  • 内科学
  • 内分泌学、糖尿病および代謝内科学
  • 内分泌学


「A case of diabetic ketoacidosis in a type 2 diabetic patient accompanied by Plummer's disease」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。