TY - JOUR
T1 - A case of fibrous papule of the nose with abundant hair follicular structures
AU - Kita, Kazuyo
AU - Kato, Shiori
AU - Kido-Nakahara, Makiko
AU - Nakahara, Takeshi
AU - Moroi, Yoichi
AU - Kiryu, Hiromaro
AU - Furue, Masutaka
PY - 2014
Y1 - 2014
N2 - A 68-year-old male presented with a 10-year history of a pedunculated nodule on his nose. Dermoscopy showed a white hair and a brownish pseudopigmented network-like structure. A histopathological analysis of the lesion revealed a proliferation of collagen fibers and dilatation and proliferation of capillaries associated with occasional satellite cells, which were immunohistochemically positive for factor XIIIa and CD34, and negative for S-100 protein. Based upon these findings, a diagnosis of fibrous papule of the nose was suggested. However, there were areas of aggregation of mature and immature hair follicles with surrounding clefts dividing fibrofollicular units from one another in superficial parts of the upper dermis. We therefore diagnosed this case as a fibrous papule of the nose with abundant hair follicular structures. Our case would support the theory that fibrous papule of the nose probably represents a proliferative reactive process of a follicular unit affected by some external stimuli.
AB - A 68-year-old male presented with a 10-year history of a pedunculated nodule on his nose. Dermoscopy showed a white hair and a brownish pseudopigmented network-like structure. A histopathological analysis of the lesion revealed a proliferation of collagen fibers and dilatation and proliferation of capillaries associated with occasional satellite cells, which were immunohistochemically positive for factor XIIIa and CD34, and negative for S-100 protein. Based upon these findings, a diagnosis of fibrous papule of the nose was suggested. However, there were areas of aggregation of mature and immature hair follicles with surrounding clefts dividing fibrofollicular units from one another in superficial parts of the upper dermis. We therefore diagnosed this case as a fibrous papule of the nose with abundant hair follicular structures. Our case would support the theory that fibrous papule of the nose probably represents a proliferative reactive process of a follicular unit affected by some external stimuli.
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U2 - 10.2336/nishinihonhifu.76.465
DO - 10.2336/nishinihonhifu.76.465
M3 - Article
AN - SCOPUS:84929619219
VL - 76
SP - 465
EP - 468
JO - Nishinihon Journal of Dermatology
JF - Nishinihon Journal of Dermatology
SN - 0386-9784
IS - 5
ER -