A case of Hopkins syndrome with onset at puberty

Akira Okayama, Hideo Hara, Hiroshi Shigeto, Takeshi Yamada, Jun Ichi Kira

研究成果: Contribution to journalArticle査読

2 被引用数 (Scopus)

抄録

The patient was a 15-year-old man who developed weakness of left leg 6 days after an acute asthmatic attack. Neurological examination revealed severe muscle weakness and atrophy at L5-S1 level and mild muscle weakness and atrophy at L2-4 level in the left leg. Deep tendon reflexes were normal in the upper limbs and slightly brisk in the lower limbs except for absence of Achilles tendon reflex on the left. His sensation was normal. Needle EMG revealed neurogenic changes in both the left (L2-S1) and right (L2-4) leg muscles. Motor nerve conduction study of the left tibial and peroneal nerves revealed a marked reduction of amplitude and mild reduction of MCV. F-wave was not evoked in either nerves. Sensory nerve conduction study of the left sural nerve was normal. The titers of anti-viral antibodies in the paired sera showed no significant changes in any viruses examined including echovirus, enterovirus, coxsackievirus and poliovirus type 1, 2 and 3. The serum IgE was elevated (1,300 IU/ml) and mite antigen-specific IgE was strongly positive. Spinal cord MRI revealed no abnormality in either thoracic or lumbar spinal cord. This patient was diagnosed a sa rare case of Hopkins syndrome with onset at puberty.

本文言語英語
ページ(範囲)452-455
ページ数4
ジャーナルClinical Neurology
39
4
出版ステータス出版済み - 4 1 1999

All Science Journal Classification (ASJC) codes

  • Clinical Neurology

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