A case of intracranial solitary fibrous tumor/hemangiopericytoma with dedifferentiated component

Akira Maekawa; Kenichi Kohashi; Yuichi Yamada; Akira Nakamizo; Koji Yoshimoto; Masahiro Mizoguchi; Toru Iwaki; Yoshinao Oda

doi:10.1111/neup.12181

A case of intracranial solitary fibrous tumor/hemangiopericytoma with dedifferentiated component

Akira Maekawa, Kenichi Kohashi, Yuichi Yamada, Akira Nakamizo, Koji Yoshimoto, Masahiro Mizoguchi, Toru Iwaki, Yoshinao Oda

研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

9 被引用数 (Scopus)

抄録

We report the case of a 51-year-old Japanese man with an intracranial dedifferentiated solitary fibrous tumor/hemangiopericytoma (SFT/HPC) identified morphologically and immunohistochemically, comprised of a typical SFT/HPC with a high-grade pleomorphic component. NAB2-STAT6 fusion transcripts were detected by reverse transcriptase polymerase chain reaction in both the conventional and high-grade components. The tumor cells in both components showed the nuclear expression of STAT6 protein, indicating the diagnostic value of these examinations. Intracranial dedifferentiated SFT/HPC is a very rare but important differential diagnosis in intracranial pleomorphic tumors.

本文言語	英語
ページ（範囲）	260-265
ページ数	6
ジャーナル	Neuropathology
巻	35
号	3
DOI	https://doi.org/10.1111/neup.12181
出版ステータス	出版済み - 6月 1 2015

All Science Journal Classification (ASJC) codes

病理学および法医学
臨床神経学

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10.1111/neup.12181

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abstract = "We report the case of a 51-year-old Japanese man with an intracranial dedifferentiated solitary fibrous tumor/hemangiopericytoma (SFT/HPC) identified morphologically and immunohistochemically, comprised of a typical SFT/HPC with a high-grade pleomorphic component. NAB2-STAT6 fusion transcripts were detected by reverse transcriptase polymerase chain reaction in both the conventional and high-grade components. The tumor cells in both components showed the nuclear expression of STAT6 protein, indicating the diagnostic value of these examinations. Intracranial dedifferentiated SFT/HPC is a very rare but important differential diagnosis in intracranial pleomorphic tumors.",

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AU - Maekawa, Akira

AU - Kohashi, Kenichi

AU - Yamada, Yuichi

AU - Nakamizo, Akira

AU - Yoshimoto, Koji

AU - Mizoguchi, Masahiro

AU - Iwaki, Toru

AU - Oda, Yoshinao

PY - 2015/6/1

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N2 - We report the case of a 51-year-old Japanese man with an intracranial dedifferentiated solitary fibrous tumor/hemangiopericytoma (SFT/HPC) identified morphologically and immunohistochemically, comprised of a typical SFT/HPC with a high-grade pleomorphic component. NAB2-STAT6 fusion transcripts were detected by reverse transcriptase polymerase chain reaction in both the conventional and high-grade components. The tumor cells in both components showed the nuclear expression of STAT6 protein, indicating the diagnostic value of these examinations. Intracranial dedifferentiated SFT/HPC is a very rare but important differential diagnosis in intracranial pleomorphic tumors.

AB - We report the case of a 51-year-old Japanese man with an intracranial dedifferentiated solitary fibrous tumor/hemangiopericytoma (SFT/HPC) identified morphologically and immunohistochemically, comprised of a typical SFT/HPC with a high-grade pleomorphic component. NAB2-STAT6 fusion transcripts were detected by reverse transcriptase polymerase chain reaction in both the conventional and high-grade components. The tumor cells in both components showed the nuclear expression of STAT6 protein, indicating the diagnostic value of these examinations. Intracranial dedifferentiated SFT/HPC is a very rare but important differential diagnosis in intracranial pleomorphic tumors.

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A case of intracranial solitary fibrous tumor/hemangiopericytoma with dedifferentiated component

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