A case of late onset myoclonic epilepsy in Down syndrome (LOMEDS)

研究成果: Contribution to journalArticle査読

抄録

Myoclonic epilepsy is being increasingly recognized as a late onset complication in middle-aged or elderly patients with Down syndrome, in association with acute cognitive decline or dementia. We report a case of late onset myoclonic epilepsy in Down syndrome (LOMEDS) with acute cognitive decline, aged 45 year-olds. Although her intelligence condition remained poor with one to two-words sentences and difficult in following commands even after treatment, induction of levetiracetam and lamotorigin resulted in rapid, sustained seizure freedom and upgrading social activity with no adverse events. A combination of levetiracetam and lamotorigin appear to be effective for LOMEDS, and could be considered as first line agents for this special condition.

本文言語英語
ページ(範囲)564-567
ページ数4
ジャーナルJournal of the Japan Epilepsy Society
32
3
DOI
出版ステータス出版済み - 2015

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology

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