A case of poisoning in a man who drank a nutrition supplement containing methomyl, a carbamate pesticide.

Keiko Kudo, Yoshihiro Hida, Akinori Zaitsu, Hiromasa Inoue, Akiko Tsuji, Tomomi Ishida, Noriaki Ikeda

研究成果: Contribution to journalArticle査読

3 被引用数 (Scopus)

抄録

A 50-year-old man was admitted to the emergency room complaining oppression on his chest, sweating and vomiting. He had drunk a 30 ml volume nutrition supplement 60 minutes before. As myosis and decrease of serum choline esterase activity were observed on admission examination, poisoning was suspected and toxicological analyses were carried out on the heeltap of the drink. Drug screening by gas chromatography-mass spectrometry (GC/MS) revealed the presence of methomyl and the concentration of methomyl in the heeltap determined by liquid chromatography was 2.1 mg/ml. Methomyl concentrations in the serum and urine were determined after converting methomyl to its oxime form followed by derivatization and GC/MS. Methomyl concentration in the serum collected 6 hours after ingestion was 0.63 microg/ml, and that in the urine collected 7-20 hours after ingestion was 0.10 microg/ml. Based on these values and reported data, the amount of methomyl contaminated to the drink was considered to be a toxic dose.

本文言語英語
ページ(範囲)305-310
ページ数6
ジャーナルFukuoka igaku zasshi = Hukuoka acta medica
96
7
出版ステータス出版済み - 7 2005

All Science Journal Classification (ASJC) codes

  • 医学(全般)

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