A case of protein-losing gastroenteropathy accompanied by Sjögren syndrome and mixed connective tissue disease

Kana Kakigao, Nobuyoshi Fukushima, Takahiro Mizutani, Kazuhiro Haraguchi, Risa Okamoto, Noriko Sawamura, Tomoko Oohashi, Aya Mitsuyasu, Takashi Fujiyama, Tsuyoshi Yoshimoto, Motoyuki Koujima, Ken Kawabe, Kunitaka Fukuizumi, Makoto Nakamuta, Naohiko Harada

研究成果: ジャーナルへの寄稿記事

4 引用 (Scopus)

抄録

Case reports of protein-losing gastroenteropathy (PLGE) associated with not only mixed connective tissue disease (MCTD) but also Sjögren syndrome (SjS) are very rare. We report a first case of PLGE in a patient with both MCTD and SjS. A 58-year-old Japanese woman was referred and admitted to our hospital because of abdominal fullness and lower leg edema Her past medical history revealed SjS at age 40. Physical examination demonstrated lower leg edema and Raynaud's phenomenon. Blood chemistry data showed severe hypoproteinemia. Anti RNP antibody was positive. MCTD was diagnosed. The alpha-1 antitrypsin clearance level was high. The 99mTc-DTPA human serum albumin scintigraphy demonstrated abnormal accumulation in the intestine. PLGE associated with both MCTD and SjS was diagnosed, but she was successfully treated by prednisolone.

元の言語英語
ページ(範囲)1770-1775
ページ数6
ジャーナルJournal of Japanese Society of Gastroenterology
109
発行部数10
出版物ステータス出版済み - 10 1 2012

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Mixed Connective Tissue Disease
Edema
Leg
Proteins
Technetium Tc 99m Aggregated Albumin
Hypoproteinemia
alpha 1-Antitrypsin
Pentetic Acid
Raynaud Disease
Prednisolone
Radionuclide Imaging
Physical Examination
Intestines
Anti-Idiotypic Antibodies

All Science Journal Classification (ASJC) codes

  • Gastroenterology

これを引用

Kakigao, K., Fukushima, N., Mizutani, T., Haraguchi, K., Okamoto, R., Sawamura, N., ... Harada, N. (2012). A case of protein-losing gastroenteropathy accompanied by Sjögren syndrome and mixed connective tissue disease. Journal of Japanese Society of Gastroenterology, 109(10), 1770-1775.

A case of protein-losing gastroenteropathy accompanied by Sjögren syndrome and mixed connective tissue disease. / Kakigao, Kana; Fukushima, Nobuyoshi; Mizutani, Takahiro; Haraguchi, Kazuhiro; Okamoto, Risa; Sawamura, Noriko; Oohashi, Tomoko; Mitsuyasu, Aya; Fujiyama, Takashi; Yoshimoto, Tsuyoshi; Koujima, Motoyuki; Kawabe, Ken; Fukuizumi, Kunitaka; Nakamuta, Makoto; Harada, Naohiko.

:: Journal of Japanese Society of Gastroenterology, 巻 109, 番号 10, 01.10.2012, p. 1770-1775.

研究成果: ジャーナルへの寄稿記事

Kakigao, K, Fukushima, N, Mizutani, T, Haraguchi, K, Okamoto, R, Sawamura, N, Oohashi, T, Mitsuyasu, A, Fujiyama, T, Yoshimoto, T, Koujima, M, Kawabe, K, Fukuizumi, K, Nakamuta, M & Harada, N 2012, 'A case of protein-losing gastroenteropathy accompanied by Sjögren syndrome and mixed connective tissue disease', Journal of Japanese Society of Gastroenterology, 巻. 109, 番号 10, pp. 1770-1775.
Kakigao K, Fukushima N, Mizutani T, Haraguchi K, Okamoto R, Sawamura N その他. A case of protein-losing gastroenteropathy accompanied by Sjögren syndrome and mixed connective tissue disease. Journal of Japanese Society of Gastroenterology. 2012 10 1;109(10):1770-1775.
Kakigao, Kana ; Fukushima, Nobuyoshi ; Mizutani, Takahiro ; Haraguchi, Kazuhiro ; Okamoto, Risa ; Sawamura, Noriko ; Oohashi, Tomoko ; Mitsuyasu, Aya ; Fujiyama, Takashi ; Yoshimoto, Tsuyoshi ; Koujima, Motoyuki ; Kawabe, Ken ; Fukuizumi, Kunitaka ; Nakamuta, Makoto ; Harada, Naohiko. / A case of protein-losing gastroenteropathy accompanied by Sjögren syndrome and mixed connective tissue disease. :: Journal of Japanese Society of Gastroenterology. 2012 ; 巻 109, 番号 10. pp. 1770-1775.
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abstract = "Case reports of protein-losing gastroenteropathy (PLGE) associated with not only mixed connective tissue disease (MCTD) but also Sj{\"o}gren syndrome (SjS) are very rare. We report a first case of PLGE in a patient with both MCTD and SjS. A 58-year-old Japanese woman was referred and admitted to our hospital because of abdominal fullness and lower leg edema Her past medical history revealed SjS at age 40. Physical examination demonstrated lower leg edema and Raynaud's phenomenon. Blood chemistry data showed severe hypoproteinemia. Anti RNP antibody was positive. MCTD was diagnosed. The alpha-1 antitrypsin clearance level was high. The 99mTc-DTPA human serum albumin scintigraphy demonstrated abnormal accumulation in the intestine. PLGE associated with both MCTD and SjS was diagnosed, but she was successfully treated by prednisolone.",
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AU - Kakigao, Kana

AU - Fukushima, Nobuyoshi

AU - Mizutani, Takahiro

AU - Haraguchi, Kazuhiro

AU - Okamoto, Risa

AU - Sawamura, Noriko

AU - Oohashi, Tomoko

AU - Mitsuyasu, Aya

AU - Fujiyama, Takashi

AU - Yoshimoto, Tsuyoshi

AU - Koujima, Motoyuki

AU - Kawabe, Ken

AU - Fukuizumi, Kunitaka

AU - Nakamuta, Makoto

AU - Harada, Naohiko

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N2 - Case reports of protein-losing gastroenteropathy (PLGE) associated with not only mixed connective tissue disease (MCTD) but also Sjögren syndrome (SjS) are very rare. We report a first case of PLGE in a patient with both MCTD and SjS. A 58-year-old Japanese woman was referred and admitted to our hospital because of abdominal fullness and lower leg edema Her past medical history revealed SjS at age 40. Physical examination demonstrated lower leg edema and Raynaud's phenomenon. Blood chemistry data showed severe hypoproteinemia. Anti RNP antibody was positive. MCTD was diagnosed. The alpha-1 antitrypsin clearance level was high. The 99mTc-DTPA human serum albumin scintigraphy demonstrated abnormal accumulation in the intestine. PLGE associated with both MCTD and SjS was diagnosed, but she was successfully treated by prednisolone.

AB - Case reports of protein-losing gastroenteropathy (PLGE) associated with not only mixed connective tissue disease (MCTD) but also Sjögren syndrome (SjS) are very rare. We report a first case of PLGE in a patient with both MCTD and SjS. A 58-year-old Japanese woman was referred and admitted to our hospital because of abdominal fullness and lower leg edema Her past medical history revealed SjS at age 40. Physical examination demonstrated lower leg edema and Raynaud's phenomenon. Blood chemistry data showed severe hypoproteinemia. Anti RNP antibody was positive. MCTD was diagnosed. The alpha-1 antitrypsin clearance level was high. The 99mTc-DTPA human serum albumin scintigraphy demonstrated abnormal accumulation in the intestine. PLGE associated with both MCTD and SjS was diagnosed, but she was successfully treated by prednisolone.

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