A case of protein-losing gastroenteropathy accompanied by Sjögren syndrome and mixed connective tissue disease

Kana Kakigao; Nobuyoshi Fukushima; Takahiro Mizutani; Kazuhiro Haraguchi; Risa Okamoto; Noriko Sawamura; Tomoko Oohashi; Aya Mitsuyasu; Takashi Fujiyama; Tsuyoshi Yoshimoto; Motoyuki Koujima; Ken Kawabe; Kunitaka Fukuizumi; Makoto Nakamuta; Naohiko Harada

A case of protein-losing gastroenteropathy accompanied by Sjögren syndrome and mixed connective tissue disease

Kana Kakigao, Nobuyoshi Fukushima, Takahiro Mizutani, Kazuhiro Haraguchi, Risa Okamoto, Noriko Sawamura, Tomoko Oohashi, Aya Mitsuyasu, Takashi Fujiyama, Tsuyoshi Yoshimoto, Motoyuki Koujima, Ken Kawabe, Kunitaka Fukuizumi, Makoto Nakamuta, Naohiko Harada

研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

6 被引用数 (Scopus)

抄録

Case reports of protein-losing gastroenteropathy (PLGE) associated with not only mixed connective tissue disease (MCTD) but also Sjögren syndrome (SjS) are very rare. We report a first case of PLGE in a patient with both MCTD and SjS. A 58-year-old Japanese woman was referred and admitted to our hospital because of abdominal fullness and lower leg edema Her past medical history revealed SjS at age 40. Physical examination demonstrated lower leg edema and Raynaud's phenomenon. Blood chemistry data showed severe hypoproteinemia. Anti RNP antibody was positive. MCTD was diagnosed. The alpha-1 antitrypsin clearance level was high. The ^99mTc-DTPA human serum albumin scintigraphy demonstrated abnormal accumulation in the intestine. PLGE associated with both MCTD and SjS was diagnosed, but she was successfully treated by prednisolone.

本文言語	英語
ページ（範囲）	1770-1775
ページ数	6
ジャーナル	Journal of Japanese Society of Gastroenterology
巻	109
号	10
出版ステータス	出版済み - 10月 2012
外部発表	はい

All Science Journal Classification (ASJC) codes

消化器病学

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

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Kakigao, K., Fukushima, N., Mizutani, T., Haraguchi, K., Okamoto, R., Sawamura, N., Oohashi, T., Mitsuyasu, A., Fujiyama, T., Yoshimoto, T., Koujima, M., Kawabe, K., Fukuizumi, K., Nakamuta, M., & Harada, N. (2012). A case of protein-losing gastroenteropathy accompanied by Sjögren syndrome and mixed connective tissue disease. Journal of Japanese Society of Gastroenterology, 109(10), 1770-1775.

A case of protein-losing gastroenteropathy accompanied by Sjögren syndrome and mixed connective tissue disease. / Kakigao, Kana; Fukushima, Nobuyoshi; Mizutani, Takahiro; Haraguchi, Kazuhiro; Okamoto, Risa; Sawamura, Noriko; Oohashi, Tomoko; Mitsuyasu, Aya; Fujiyama, Takashi; Yoshimoto, Tsuyoshi; Koujima, Motoyuki; Kawabe, Ken; Fukuizumi, Kunitaka; Nakamuta, Makoto; Harada, Naohiko.

In: Journal of Japanese Society of Gastroenterology, Vol. 109, No. 10, 10.2012, p. 1770-1775.

研究成果: ジャーナルへの寄稿 › 学術誌 › 査読

Kakigao, K, Fukushima, N, Mizutani, T, Haraguchi, K, Okamoto, R, Sawamura, N, Oohashi, T, Mitsuyasu, A, Fujiyama, T, Yoshimoto, T, Koujima, M, Kawabe, K, Fukuizumi, K, Nakamuta, M & Harada, N 2012, 'A case of protein-losing gastroenteropathy accompanied by Sjögren syndrome and mixed connective tissue disease', Journal of Japanese Society of Gastroenterology, vol. 109, no. 10, pp. 1770-1775.

Kakigao, Kana ; Fukushima, Nobuyoshi ; Mizutani, Takahiro ; Haraguchi, Kazuhiro ; Okamoto, Risa ; Sawamura, Noriko ; Oohashi, Tomoko ; Mitsuyasu, Aya ; Fujiyama, Takashi ; Yoshimoto, Tsuyoshi ; Koujima, Motoyuki ; Kawabe, Ken ; Fukuizumi, Kunitaka ; Nakamuta, Makoto ; Harada, Naohiko. / A case of protein-losing gastroenteropathy accompanied by Sjögren syndrome and mixed connective tissue disease. In: Journal of Japanese Society of Gastroenterology. 2012 ; Vol. 109, No. 10. pp. 1770-1775.

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abstract = "Case reports of protein-losing gastroenteropathy (PLGE) associated with not only mixed connective tissue disease (MCTD) but also Sj{\"o}gren syndrome (SjS) are very rare. We report a first case of PLGE in a patient with both MCTD and SjS. A 58-year-old Japanese woman was referred and admitted to our hospital because of abdominal fullness and lower leg edema Her past medical history revealed SjS at age 40. Physical examination demonstrated lower leg edema and Raynaud's phenomenon. Blood chemistry data showed severe hypoproteinemia. Anti RNP antibody was positive. MCTD was diagnosed. The alpha-1 antitrypsin clearance level was high. The 99mTc-DTPA human serum albumin scintigraphy demonstrated abnormal accumulation in the intestine. PLGE associated with both MCTD and SjS was diagnosed, but she was successfully treated by prednisolone.",

author = "Kana Kakigao and Nobuyoshi Fukushima and Takahiro Mizutani and Kazuhiro Haraguchi and Risa Okamoto and Noriko Sawamura and Tomoko Oohashi and Aya Mitsuyasu and Takashi Fujiyama and Tsuyoshi Yoshimoto and Motoyuki Koujima and Ken Kawabe and Kunitaka Fukuizumi and Makoto Nakamuta and Naohiko Harada",

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AU - Kakigao, Kana

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AU - Okamoto, Risa

AU - Sawamura, Noriko

AU - Oohashi, Tomoko

AU - Mitsuyasu, Aya

AU - Fujiyama, Takashi

AU - Yoshimoto, Tsuyoshi

AU - Koujima, Motoyuki

AU - Kawabe, Ken

AU - Fukuizumi, Kunitaka

AU - Nakamuta, Makoto

AU - Harada, Naohiko

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N2 - Case reports of protein-losing gastroenteropathy (PLGE) associated with not only mixed connective tissue disease (MCTD) but also Sjögren syndrome (SjS) are very rare. We report a first case of PLGE in a patient with both MCTD and SjS. A 58-year-old Japanese woman was referred and admitted to our hospital because of abdominal fullness and lower leg edema Her past medical history revealed SjS at age 40. Physical examination demonstrated lower leg edema and Raynaud's phenomenon. Blood chemistry data showed severe hypoproteinemia. Anti RNP antibody was positive. MCTD was diagnosed. The alpha-1 antitrypsin clearance level was high. The 99mTc-DTPA human serum albumin scintigraphy demonstrated abnormal accumulation in the intestine. PLGE associated with both MCTD and SjS was diagnosed, but she was successfully treated by prednisolone.

AB - Case reports of protein-losing gastroenteropathy (PLGE) associated with not only mixed connective tissue disease (MCTD) but also Sjögren syndrome (SjS) are very rare. We report a first case of PLGE in a patient with both MCTD and SjS. A 58-year-old Japanese woman was referred and admitted to our hospital because of abdominal fullness and lower leg edema Her past medical history revealed SjS at age 40. Physical examination demonstrated lower leg edema and Raynaud's phenomenon. Blood chemistry data showed severe hypoproteinemia. Anti RNP antibody was positive. MCTD was diagnosed. The alpha-1 antitrypsin clearance level was high. The 99mTc-DTPA human serum albumin scintigraphy demonstrated abnormal accumulation in the intestine. PLGE associated with both MCTD and SjS was diagnosed, but she was successfully treated by prednisolone.

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A case of protein-losing gastroenteropathy accompanied by Sjögren syndrome and mixed connective tissue disease

抄録

All Science Journal Classification (ASJC) codes

UN SDG

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