A case of protein-losing gastroenteropathy accompanied by Sjögren syndrome and mixed connective tissue disease

Kana Kakigao; Nobuyoshi Fukushima; Takahiro Mizutani; Kazuhiro Haraguchi; Risa Okamoto; Noriko Sawamura; Tomoko Oohashi; Aya Mitsuyasu; Takashi Fujiyama; Tsuyoshi Yoshimoto; Motoyuki Koujima; Ken Kawabe; Kunitaka Fukuizumi; Makoto Nakamuta; Naohiko Harada

A case of protein-losing gastroenteropathy accompanied by Sjögren syndrome and mixed connective tissue disease

Kana Kakigao, Nobuyoshi Fukushima, Takahiro Mizutani, Kazuhiro Haraguchi, Risa Okamoto, Noriko Sawamura, Tomoko Oohashi, Aya Mitsuyasu, Takashi Fujiyama, Tsuyoshi Yoshimoto, Motoyuki Koujima, Ken Kawabe, Kunitaka Fukuizumi, Makoto Nakamuta, Naohiko Harada

肝臓・膵臓・胆道内科

研究成果: Contribution to journal › Article › 査読

6 被引用数 (Scopus)

抄録

Case reports of protein-losing gastroenteropathy (PLGE) associated with not only mixed connective tissue disease (MCTD) but also Sjögren syndrome (SjS) are very rare. We report a first case of PLGE in a patient with both MCTD and SjS. A 58-year-old Japanese woman was referred and admitted to our hospital because of abdominal fullness and lower leg edema Her past medical history revealed SjS at age 40. Physical examination demonstrated lower leg edema and Raynaud's phenomenon. Blood chemistry data showed severe hypoproteinemia. Anti RNP antibody was positive. MCTD was diagnosed. The alpha-1 antitrypsin clearance level was high. The ^99mTc-DTPA human serum albumin scintigraphy demonstrated abnormal accumulation in the intestine. PLGE associated with both MCTD and SjS was diagnosed, but she was successfully treated by prednisolone.

本文言語	英語
ページ（範囲）	1770-1775
ページ数	6
ジャーナル	Journal of Japanese Society of Gastroenterology
巻	109
号	10
出版ステータス	出版済み - 10 2012

All Science Journal Classification (ASJC) codes

Gastroenterology

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引用スタイル

Kakigao, K., Fukushima, N., Mizutani, T., Haraguchi, K., Okamoto, R., Sawamura, N., Oohashi, T., Mitsuyasu, A., Fujiyama, T., Yoshimoto, T., Koujima, M., Kawabe, K., Fukuizumi, K., Nakamuta, M., & Harada, N. (2012). A case of protein-losing gastroenteropathy accompanied by Sjögren syndrome and mixed connective tissue disease. Journal of Japanese Society of Gastroenterology, 109(10), 1770-1775.

A case of protein-losing gastroenteropathy accompanied by Sjögren syndrome and mixed connective tissue disease. / Kakigao, Kana; Fukushima, Nobuyoshi; Mizutani, Takahiro; Haraguchi, Kazuhiro; Okamoto, Risa; Sawamura, Noriko; Oohashi, Tomoko; Mitsuyasu, Aya; Fujiyama, Takashi; Yoshimoto, Tsuyoshi; Koujima, Motoyuki; Kawabe, Ken; Fukuizumi, Kunitaka; Nakamuta, Makoto; Harada, Naohiko.

In: Journal of Japanese Society of Gastroenterology, Vol. 109, No. 10, 10.2012, p. 1770-1775.

研究成果: Contribution to journal › Article › 査読

Kakigao, K, Fukushima, N, Mizutani, T, Haraguchi, K, Okamoto, R, Sawamura, N, Oohashi, T, Mitsuyasu, A, Fujiyama, T, Yoshimoto, T, Koujima, M, Kawabe, K, Fukuizumi, K, Nakamuta, M & Harada, N 2012, 'A case of protein-losing gastroenteropathy accompanied by Sjögren syndrome and mixed connective tissue disease', Journal of Japanese Society of Gastroenterology, vol. 109, no. 10, pp. 1770-1775.

Kakigao, Kana ; Fukushima, Nobuyoshi ; Mizutani, Takahiro ; Haraguchi, Kazuhiro ; Okamoto, Risa ; Sawamura, Noriko ; Oohashi, Tomoko ; Mitsuyasu, Aya ; Fujiyama, Takashi ; Yoshimoto, Tsuyoshi ; Koujima, Motoyuki ; Kawabe, Ken ; Fukuizumi, Kunitaka ; Nakamuta, Makoto ; Harada, Naohiko. / A case of protein-losing gastroenteropathy accompanied by Sjögren syndrome and mixed connective tissue disease. In: Journal of Japanese Society of Gastroenterology. 2012 ; Vol. 109, No. 10. pp. 1770-1775.

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abstract = "Case reports of protein-losing gastroenteropathy (PLGE) associated with not only mixed connective tissue disease (MCTD) but also Sj{\"o}gren syndrome (SjS) are very rare. We report a first case of PLGE in a patient with both MCTD and SjS. A 58-year-old Japanese woman was referred and admitted to our hospital because of abdominal fullness and lower leg edema Her past medical history revealed SjS at age 40. Physical examination demonstrated lower leg edema and Raynaud's phenomenon. Blood chemistry data showed severe hypoproteinemia. Anti RNP antibody was positive. MCTD was diagnosed. The alpha-1 antitrypsin clearance level was high. The 99mTc-DTPA human serum albumin scintigraphy demonstrated abnormal accumulation in the intestine. PLGE associated with both MCTD and SjS was diagnosed, but she was successfully treated by prednisolone.",

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AU - Okamoto, Risa

AU - Sawamura, Noriko

AU - Oohashi, Tomoko

AU - Mitsuyasu, Aya

AU - Fujiyama, Takashi

AU - Yoshimoto, Tsuyoshi

AU - Koujima, Motoyuki

AU - Kawabe, Ken

AU - Fukuizumi, Kunitaka

AU - Nakamuta, Makoto

AU - Harada, Naohiko

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