A case of pulmonary nocardiosis associated with middle lobe atelectasis

S. Kuroki, H. Yamada, O. Katoh, Yoichi Nakanishi, M. Yamaguchi, Z. Nagasawa

研究成果: ジャーナルへの寄稿記事

1 引用 (Scopus)

抄録

Pulmonary nocardiosis is a rare disease. We reported a case of pulmonary nocardiosis associated with middle lobe atelectasis. A 66-year-old female was admitted to Saga Medical School Hospital with complaints of fever, productive cough and hemosputum. Nocardia asteroides was isolated from her sputum and bronchial lavage fluid. Administration of sulfamethoxazole-trimethoprim (ST) improved her symptoms and Nocardia asteroides were rapidly eliminated from her sputum. However, she had severe side effects of ST: toxic dermatitis, granulocytopenia and liver dysfunction, whereupon administration of ST was stopped. About two weeks later, Nocardia asteroides appeared again in her sputum. Either netilmicin (NTL) or minocycline (MINO) given consecutively could not eliminate Nocardia asteroides from her sputa. Subsequently a combination therapy of OFLX administration and gentamicin inhalation was tried. This treatment improved her symptoms and eradicated Nocardia asteroides from her sputa completely. In vitro study, ST, MINO and aminoglycosides showed good susceptibility against Nocardia asteroides. In this case, it was revealed that GM inhalation therapy is also very useful for pulmonary Nocardiosis.

元の言語英語
ページ(範囲)243-248
ページ数6
ジャーナルKansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases
64
発行部数2
DOI
出版物ステータス出版済み - 1 1 1990

Fingerprint

Nocardia asteroides
Nocardia Infections
Pulmonary Atelectasis
Sputum
Sulfamethoxazole Drug Combination Trimethoprim
Minocycline
Inhalation Administration
Netilmicin
Respiratory Therapy
Agranulocytosis
Poisons
Bronchoalveolar Lavage Fluid
Aminoglycosides
Dermatitis
Rare Diseases
Gentamicins
Medical Schools
Cough
Liver Diseases
Fever

All Science Journal Classification (ASJC) codes

  • Medicine(all)

これを引用

A case of pulmonary nocardiosis associated with middle lobe atelectasis. / Kuroki, S.; Yamada, H.; Katoh, O.; Nakanishi, Yoichi; Yamaguchi, M.; Nagasawa, Z.

:: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 巻 64, 番号 2, 01.01.1990, p. 243-248.

研究成果: ジャーナルへの寄稿記事

Kuroki, S. ; Yamada, H. ; Katoh, O. ; Nakanishi, Yoichi ; Yamaguchi, M. ; Nagasawa, Z. / A case of pulmonary nocardiosis associated with middle lobe atelectasis. :: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases. 1990 ; 巻 64, 番号 2. pp. 243-248.
@article{9b290f9ff30a476891ddf632c2fb42e4,
title = "A case of pulmonary nocardiosis associated with middle lobe atelectasis",
abstract = "Pulmonary nocardiosis is a rare disease. We reported a case of pulmonary nocardiosis associated with middle lobe atelectasis. A 66-year-old female was admitted to Saga Medical School Hospital with complaints of fever, productive cough and hemosputum. Nocardia asteroides was isolated from her sputum and bronchial lavage fluid. Administration of sulfamethoxazole-trimethoprim (ST) improved her symptoms and Nocardia asteroides were rapidly eliminated from her sputum. However, she had severe side effects of ST: toxic dermatitis, granulocytopenia and liver dysfunction, whereupon administration of ST was stopped. About two weeks later, Nocardia asteroides appeared again in her sputum. Either netilmicin (NTL) or minocycline (MINO) given consecutively could not eliminate Nocardia asteroides from her sputa. Subsequently a combination therapy of OFLX administration and gentamicin inhalation was tried. This treatment improved her symptoms and eradicated Nocardia asteroides from her sputa completely. In vitro study, ST, MINO and aminoglycosides showed good susceptibility against Nocardia asteroides. In this case, it was revealed that GM inhalation therapy is also very useful for pulmonary Nocardiosis.",
author = "S. Kuroki and H. Yamada and O. Katoh and Yoichi Nakanishi and M. Yamaguchi and Z. Nagasawa",
year = "1990",
month = "1",
day = "1",
doi = "10.11150/kansenshogakuzasshi1970.64.243",
language = "English",
volume = "64",
pages = "243--248",
journal = "Nippon Densenbyo Gakkai zasshi",
issn = "0387-5911",
publisher = "Nihon Kansensho Gakkai",
number = "2",

}

TY - JOUR

T1 - A case of pulmonary nocardiosis associated with middle lobe atelectasis

AU - Kuroki, S.

AU - Yamada, H.

AU - Katoh, O.

AU - Nakanishi, Yoichi

AU - Yamaguchi, M.

AU - Nagasawa, Z.

PY - 1990/1/1

Y1 - 1990/1/1

N2 - Pulmonary nocardiosis is a rare disease. We reported a case of pulmonary nocardiosis associated with middle lobe atelectasis. A 66-year-old female was admitted to Saga Medical School Hospital with complaints of fever, productive cough and hemosputum. Nocardia asteroides was isolated from her sputum and bronchial lavage fluid. Administration of sulfamethoxazole-trimethoprim (ST) improved her symptoms and Nocardia asteroides were rapidly eliminated from her sputum. However, she had severe side effects of ST: toxic dermatitis, granulocytopenia and liver dysfunction, whereupon administration of ST was stopped. About two weeks later, Nocardia asteroides appeared again in her sputum. Either netilmicin (NTL) or minocycline (MINO) given consecutively could not eliminate Nocardia asteroides from her sputa. Subsequently a combination therapy of OFLX administration and gentamicin inhalation was tried. This treatment improved her symptoms and eradicated Nocardia asteroides from her sputa completely. In vitro study, ST, MINO and aminoglycosides showed good susceptibility against Nocardia asteroides. In this case, it was revealed that GM inhalation therapy is also very useful for pulmonary Nocardiosis.

AB - Pulmonary nocardiosis is a rare disease. We reported a case of pulmonary nocardiosis associated with middle lobe atelectasis. A 66-year-old female was admitted to Saga Medical School Hospital with complaints of fever, productive cough and hemosputum. Nocardia asteroides was isolated from her sputum and bronchial lavage fluid. Administration of sulfamethoxazole-trimethoprim (ST) improved her symptoms and Nocardia asteroides were rapidly eliminated from her sputum. However, she had severe side effects of ST: toxic dermatitis, granulocytopenia and liver dysfunction, whereupon administration of ST was stopped. About two weeks later, Nocardia asteroides appeared again in her sputum. Either netilmicin (NTL) or minocycline (MINO) given consecutively could not eliminate Nocardia asteroides from her sputa. Subsequently a combination therapy of OFLX administration and gentamicin inhalation was tried. This treatment improved her symptoms and eradicated Nocardia asteroides from her sputa completely. In vitro study, ST, MINO and aminoglycosides showed good susceptibility against Nocardia asteroides. In this case, it was revealed that GM inhalation therapy is also very useful for pulmonary Nocardiosis.

UR - http://www.scopus.com/inward/record.url?scp=0025381564&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025381564&partnerID=8YFLogxK

U2 - 10.11150/kansenshogakuzasshi1970.64.243

DO - 10.11150/kansenshogakuzasshi1970.64.243

M3 - Article

VL - 64

SP - 243

EP - 248

JO - Nippon Densenbyo Gakkai zasshi

JF - Nippon Densenbyo Gakkai zasshi

SN - 0387-5911

IS - 2

ER -