A case of recanalized cardioembolic stroke: Possible effect of transcranial color-coded real-time sonography on thrombolytic therapy

Toshiyasu Ogata, Takanari Kitazono, Junya Kuroda, Kyoko Kamei, Masahiro Kamouchi, Hiroaki Ooboshi, Setsuro Ibayashi, Mitsuo Iida

研究成果: ジャーナルへの寄稿記事

抄録

Thrombolytic therapy appears to be one of the most valuable treatments for acute ischemic stroke. The major objective of thrombolysis in acute ischemic stroke is to recanalize occluded arteries to reestablish brain function by saving tissue from ischemic risk. Rapid lysis of intracranial clots has been strongly associated with early neurologic improvement, reduction of infarct size, and favorable outcome. It has been reported in vitro and in animal models that the combination of the administration of tissue plasminogen activator (t-PA) and the application of ultrasound was effective for thrombolysis. Moreover, Alexandrov et al have recently shown that the reperfusion rate of occluded arteries by t-PA is improved by the combined therapy with the application of ultrasound. Here we report a patient with cardioembolic stroke whose occluded middle cerebral artery (MCA) was recanalized during an examination with transcranial color-coded real-time sonography (TCCS) after thrombolytic therapy by urokinase. The combined therapy of ultrasound with urokinase may also be effective in the treatment of acute ischemic stroke.

元の言語英語
ページ(範囲)561-565
ページ数5
ジャーナルJournal of Ultrasound in Medicine
24
発行部数4
DOI
出版物ステータス出版済み - 4 2005

Fingerprint

Thrombolytic Therapy
Ultrasonography
Color
Stroke
Urokinase-Type Plasminogen Activator
Tissue Plasminogen Activator
Arteries
Middle Cerebral Artery
Therapeutics
Nervous System
Reperfusion
Animal Models
Brain

All Science Journal Classification (ASJC) codes

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

これを引用

A case of recanalized cardioembolic stroke : Possible effect of transcranial color-coded real-time sonography on thrombolytic therapy. / Ogata, Toshiyasu; Kitazono, Takanari; Kuroda, Junya; Kamei, Kyoko; Kamouchi, Masahiro; Ooboshi, Hiroaki; Ibayashi, Setsuro; Iida, Mitsuo.

:: Journal of Ultrasound in Medicine, 巻 24, 番号 4, 04.2005, p. 561-565.

研究成果: ジャーナルへの寄稿記事

Ogata, Toshiyasu ; Kitazono, Takanari ; Kuroda, Junya ; Kamei, Kyoko ; Kamouchi, Masahiro ; Ooboshi, Hiroaki ; Ibayashi, Setsuro ; Iida, Mitsuo. / A case of recanalized cardioembolic stroke : Possible effect of transcranial color-coded real-time sonography on thrombolytic therapy. :: Journal of Ultrasound in Medicine. 2005 ; 巻 24, 番号 4. pp. 561-565.
@article{44053c6870ee423eb13c2af2036cda3b,
title = "A case of recanalized cardioembolic stroke: Possible effect of transcranial color-coded real-time sonography on thrombolytic therapy",
abstract = "Thrombolytic therapy appears to be one of the most valuable treatments for acute ischemic stroke. The major objective of thrombolysis in acute ischemic stroke is to recanalize occluded arteries to reestablish brain function by saving tissue from ischemic risk. Rapid lysis of intracranial clots has been strongly associated with early neurologic improvement, reduction of infarct size, and favorable outcome. It has been reported in vitro and in animal models that the combination of the administration of tissue plasminogen activator (t-PA) and the application of ultrasound was effective for thrombolysis. Moreover, Alexandrov et al have recently shown that the reperfusion rate of occluded arteries by t-PA is improved by the combined therapy with the application of ultrasound. Here we report a patient with cardioembolic stroke whose occluded middle cerebral artery (MCA) was recanalized during an examination with transcranial color-coded real-time sonography (TCCS) after thrombolytic therapy by urokinase. The combined therapy of ultrasound with urokinase may also be effective in the treatment of acute ischemic stroke.",
author = "Toshiyasu Ogata and Takanari Kitazono and Junya Kuroda and Kyoko Kamei and Masahiro Kamouchi and Hiroaki Ooboshi and Setsuro Ibayashi and Mitsuo Iida",
year = "2005",
month = "4",
doi = "10.7863/jum.2005.24.4.561",
language = "English",
volume = "24",
pages = "561--565",
journal = "Journal of Ultrasound in Medicine",
issn = "0278-4297",
publisher = "American Institute of Ultrasound in Medicine",
number = "4",

}

TY - JOUR

T1 - A case of recanalized cardioembolic stroke

T2 - Possible effect of transcranial color-coded real-time sonography on thrombolytic therapy

AU - Ogata, Toshiyasu

AU - Kitazono, Takanari

AU - Kuroda, Junya

AU - Kamei, Kyoko

AU - Kamouchi, Masahiro

AU - Ooboshi, Hiroaki

AU - Ibayashi, Setsuro

AU - Iida, Mitsuo

PY - 2005/4

Y1 - 2005/4

N2 - Thrombolytic therapy appears to be one of the most valuable treatments for acute ischemic stroke. The major objective of thrombolysis in acute ischemic stroke is to recanalize occluded arteries to reestablish brain function by saving tissue from ischemic risk. Rapid lysis of intracranial clots has been strongly associated with early neurologic improvement, reduction of infarct size, and favorable outcome. It has been reported in vitro and in animal models that the combination of the administration of tissue plasminogen activator (t-PA) and the application of ultrasound was effective for thrombolysis. Moreover, Alexandrov et al have recently shown that the reperfusion rate of occluded arteries by t-PA is improved by the combined therapy with the application of ultrasound. Here we report a patient with cardioembolic stroke whose occluded middle cerebral artery (MCA) was recanalized during an examination with transcranial color-coded real-time sonography (TCCS) after thrombolytic therapy by urokinase. The combined therapy of ultrasound with urokinase may also be effective in the treatment of acute ischemic stroke.

AB - Thrombolytic therapy appears to be one of the most valuable treatments for acute ischemic stroke. The major objective of thrombolysis in acute ischemic stroke is to recanalize occluded arteries to reestablish brain function by saving tissue from ischemic risk. Rapid lysis of intracranial clots has been strongly associated with early neurologic improvement, reduction of infarct size, and favorable outcome. It has been reported in vitro and in animal models that the combination of the administration of tissue plasminogen activator (t-PA) and the application of ultrasound was effective for thrombolysis. Moreover, Alexandrov et al have recently shown that the reperfusion rate of occluded arteries by t-PA is improved by the combined therapy with the application of ultrasound. Here we report a patient with cardioembolic stroke whose occluded middle cerebral artery (MCA) was recanalized during an examination with transcranial color-coded real-time sonography (TCCS) after thrombolytic therapy by urokinase. The combined therapy of ultrasound with urokinase may also be effective in the treatment of acute ischemic stroke.

UR - http://www.scopus.com/inward/record.url?scp=16344387938&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=16344387938&partnerID=8YFLogxK

U2 - 10.7863/jum.2005.24.4.561

DO - 10.7863/jum.2005.24.4.561

M3 - Article

C2 - 15784776

AN - SCOPUS:16344387938

VL - 24

SP - 561

EP - 565

JO - Journal of Ultrasound in Medicine

JF - Journal of Ultrasound in Medicine

SN - 0278-4297

IS - 4

ER -