TY - JOUR
T1 - A case of secondary hemochromatosis with elevated serum interleukin-6
AU - Tsutsumi, Midori
AU - Nakamura, Misa
AU - Kawazu, Sotaro
AU - Ito, Takamichi
AU - Furue, Masutaka
PY - 2019
Y1 - 2019
N2 - Here we report a case of an 88-year-old woman with secondary hemochromatosis. Because of severe anemia, she had received blood transfusions many times in the past three years. She had a history of surgical treatments for uterine cervical cancer and rectal cancer. Her entire skin showed a progressive greyish-blue hue. Histopathologically, Berlin blue staining-positive granules were found in the dermis and the subcutaneous tissue. Ultrasound sonography, CT, and MRI revealed the deposition of iron in the liver, pancreas, and spleen, leading to the diagnosis of hemochromatosis. The concentration of interleukin-6 in serum was elevated. We speculate that the elevated serum interleukin-6 was associated with the etiology of the severe anemia and hemochromatosis in this patient.
AB - Here we report a case of an 88-year-old woman with secondary hemochromatosis. Because of severe anemia, she had received blood transfusions many times in the past three years. She had a history of surgical treatments for uterine cervical cancer and rectal cancer. Her entire skin showed a progressive greyish-blue hue. Histopathologically, Berlin blue staining-positive granules were found in the dermis and the subcutaneous tissue. Ultrasound sonography, CT, and MRI revealed the deposition of iron in the liver, pancreas, and spleen, leading to the diagnosis of hemochromatosis. The concentration of interleukin-6 in serum was elevated. We speculate that the elevated serum interleukin-6 was associated with the etiology of the severe anemia and hemochromatosis in this patient.
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U2 - 10.2336/nishinihonhifu.81.106
DO - 10.2336/nishinihonhifu.81.106
M3 - Article
AN - SCOPUS:85071902012
VL - 81
SP - 106
EP - 109
JO - Nishinihon Journal of Dermatology
JF - Nishinihon Journal of Dermatology
SN - 0386-9784
IS - 2
ER -