We report the case of a 70-year-old man who showed an elastic-soft, solid tumor of his left nasal ala and cheek. Histopathological examination showed that the tumor was filled with myxoid material and surrounded by fibrous tissue. The tumor consisted of small thin-walled blood vessels and spindle-shaped cells. Immunohistochemically, the tumor cells were negative for S-100 protein, alpha-smooth muscle actin, and desmin, while they were positive for CD34. Based on these clinical and histologic findings, we diagnosed the tumor as a superficial angiomyxoma. Carney complex is characterized by the triad of myxomas, endocrine overactivity and spotty pigmentation. The most serious component of Carney complex is cardiac myxoma. The appearance of a superficial angiomyxoma warrants an echocardiogram to rule out the presence of cardiac myxoma.
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