A case of Turner syndrome (46XXP-/45X) complicated with Crohn's disease after hormone therapy

Yutaro Ihara, Kazuoki Hizawa, Kouhei Fujita, Masahiro Iida, Ema Washio, Takahiro Kai, Tomoki Nitahata, Motohiro Esaki, Mitsuo Iida

研究成果: Contribution to journalArticle査読

抄録

A 19-year-old woman, who had been receiving hormone replacement therapy for 13 months before the diagnosis of mosaic Turner syndrome (46XXp-/45X), developed Crohn's colitis and erythema nodosum of the lower legs. Colonoscopy revealed an anal fistula and the presence of deep longitudinal ulcers with cobblestoning in the colorectum. Therapy with prednisolone and adalimumab was effective for the intestinal and skin lesions. To date, all seven case reports of Turner syndrome in Japan have also developed Crohn's disease after hormone therapy, suggesting a possible association of sex hormones in the pathogenesis.

本文言語英語
ページ(範囲)445-449
ページ数5
ジャーナルJournal of Japanese Society of Gastroenterology
114
3
出版ステータス出版済み - 2017

All Science Journal Classification (ASJC) codes

  • Gastroenterology

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