A case of virchow's lymph node recurrence of gastric cancer who had underwent gastrectomy, and treated with S-1 monotherapy leading to complete response (CR)

We report the case of a 67-year-old male with Virchow's lymph node recurrence of gastric cancer, who underwent distal gastrectomy for type 2 forecourt part of pylorus gastric cancer, showing complete response (CR) in response to S-1 monotherapy. The tumor was pathologically diagnosed as Stage IIIb (well to poorly differentiated adenocarcinoma, T3 [SE], N2 [20/51], MO). Virchow's lymph node metastasis was confirmed 2 months after surgery. One week after S-1 administration, a reduction in lymph node size was observed. After 5 courses of S-1 monotherapy, he achieved CR. The patient maintained CR for 2 years, before we switched to uracil and tegaf ur (UFT) monotherapy. The patient maintained CR for 2 years, after which UFT was discontinued. No relapse was observed 22 months after discontinuation.