A case report of neuroendocrine carcinoma of the stomach with liver metastases curatively resected after neoadjuvant chemotherapy

Kentaro Hokonohara, Akihiro Takata, Takehiro Noda, Hiroshi Imamura, Masashi Hirota, Kazuteru Oshima, Tsukasa Tanida, Hisanori Hatano, Takamichi Komori, Shunji Morita, Takashi Iwazawa, Kenzo Akagi, Shiro Adachi, Keizo Dono

研究成果: Contribution to journalArticle査読

1 被引用数 (Scopus)

抄録

The patient was a 73-year-old male with advanced gastric cancer in the lesser curvature of the antrum. Abdominal computed tomography revealed multiple liver metastases (S5, SB). He was diagnosed with clinical Stage IV gastric cancer (cT3N0M1H1) He received 3 courses of combined neoadjuvant chemotherapy with capecitabine, cisplatin, and trastuzumab because immunostaining indicated the tumor was human epidermal growth factor receptor 2 (HER2)-positive. The therapeutic response as assessed by imaging studies, was partial for the primary lesions and stable for liver metastases. Distal gastrectomy D2 lymph node dissection, and S5 extended subsegmentectomy of the liver were performed. Histopathological findings indicated that both the primary tumor and liver metastases were neuroendocrine carcinoma. The patient declined post-operative adjuvant chemotherapy and he is alive 6 months after the surgery with no evidence of recurrence. Surgery with neoadjuvant chemotherapy appears to be a promising option for advanced gastric cancer with liver metastases.

本文言語英語
ページ(範囲)2287-2289
ページ数3
ジャーナルJapanese Journal of Cancer and Chemotherapy
41
12
出版ステータス出版済み - 11 2014
外部発表はい

All Science Journal Classification (ASJC) codes

  • 腫瘍学
  • 癌研究

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