A case report of the primary double cancers of duodenum and pancreas

Primary double cancers of the duodenum and pancreas are rare, and we found only one case described previously when we surveyed the literature. We report the case of a 61-year-old man with primary double cancers of the duodenal 3^rd portion and pancreatic body. Abdominal CT showed a duodenal tumor and a separate tumor in the pancreatic body, necessitating a pancreatoduodenectomy. Histologically, the duodenal tumor was adenocarcinoma and the pancreatic tumor was invassive ductal carcinoma. These tumors were not continuous macroscopically, in pathological examination. Cytokeratin 7 found on immunohistological examination showed that the duodenal cancer origin was differed from the pancreatic cancer. Based on these findings, the definitive diagnosis was synchronous double cancers of the duodenum and pancreas. This is, to our knowledge, the first such confirmed case confirmed in immunohistological examination with Cytokeratin 7.