抄録
The authors present an extremely rare case of a fibrotic nodule arising from the cerebellopontine (CP) angle. A 57-year-old male had suffered from hearing disturbance and tinnitus for several years. Computed tomography revealed a high-density mass in the left CP angle with little enhancement after intravenous administration of contrast media. Magnetic resonance imaging (MRI) showed a very hypointense mass on T2-weighted imaging. T1-weighted MRI with gadolinium revealed very faint, delayed enhancement of the tumor. The patient underwent surgical resection of the tumor. Histopathologically the lesion comprised entirely fibrotic tissue consisting of thick collagenous fibers and sclerosing blood vessels with a few intervening viable cells with, partly, the immunophenotype of arachnoid cells. Intracranial fibrotic nodules are extremely rare. This tumor, however, had some radiological features similar to those of other, more common, tumors for example meningiomas or solitary fibrous tumors; it was, therefore, difficult to distinguish it from the others. It is believed that intracranial fibrotic nodules usually have benign, non-neoplastic characteristics, although their natural history is not yet fully understood. It is, therefore, necessary to be able to perform a differential diagnosis that will distinguish this rare condition from other intracranial fibrous neoplasms that occasionally have malignant features.
| 元の言語 | 英語 |
|---|---|
| ページ（範囲） | 122-127 |
| ページ数 | 6 |
| ジャーナル | Brain Tumor Pathology |
| 巻 | 30 |
| 発行部数 | 2 |
| DOI | |
| 出版物ステータス | 出版済み - 4 1 2013 |
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All Science Journal Classification (ASJC) codes
- Oncology
- Clinical Neurology
- Cancer Research
これを引用
A fibrotic nodule arising from the cerebellopontine angle. / Amano, Toshiyuki; Suzuki, Satoshi; Mizoguchi, Masahiro; Yoshimoto, Koji; Nakamizo, Akira; Murata, Hideki; Iwaki, Toru; Sasaki, Tomio.
：: Brain Tumor Pathology, 巻 30, 番号 2, 01.04.2013, p. 122-127.研究成果: ジャーナルへの寄稿 › 記事
}
TY - JOUR
T1 - A fibrotic nodule arising from the cerebellopontine angle
AU - Amano, Toshiyuki
AU - Suzuki, Satoshi
AU - Mizoguchi, Masahiro
AU - Yoshimoto, Koji
AU - Nakamizo, Akira
AU - Murata, Hideki
AU - Iwaki, Toru
AU - Sasaki, Tomio
PY - 2013/4/1
Y1 - 2013/4/1
N2 - The authors present an extremely rare case of a fibrotic nodule arising from the cerebellopontine (CP) angle. A 57-year-old male had suffered from hearing disturbance and tinnitus for several years. Computed tomography revealed a high-density mass in the left CP angle with little enhancement after intravenous administration of contrast media. Magnetic resonance imaging (MRI) showed a very hypointense mass on T2-weighted imaging. T1-weighted MRI with gadolinium revealed very faint, delayed enhancement of the tumor. The patient underwent surgical resection of the tumor. Histopathologically the lesion comprised entirely fibrotic tissue consisting of thick collagenous fibers and sclerosing blood vessels with a few intervening viable cells with, partly, the immunophenotype of arachnoid cells. Intracranial fibrotic nodules are extremely rare. This tumor, however, had some radiological features similar to those of other, more common, tumors for example meningiomas or solitary fibrous tumors; it was, therefore, difficult to distinguish it from the others. It is believed that intracranial fibrotic nodules usually have benign, non-neoplastic characteristics, although their natural history is not yet fully understood. It is, therefore, necessary to be able to perform a differential diagnosis that will distinguish this rare condition from other intracranial fibrous neoplasms that occasionally have malignant features.
AB - The authors present an extremely rare case of a fibrotic nodule arising from the cerebellopontine (CP) angle. A 57-year-old male had suffered from hearing disturbance and tinnitus for several years. Computed tomography revealed a high-density mass in the left CP angle with little enhancement after intravenous administration of contrast media. Magnetic resonance imaging (MRI) showed a very hypointense mass on T2-weighted imaging. T1-weighted MRI with gadolinium revealed very faint, delayed enhancement of the tumor. The patient underwent surgical resection of the tumor. Histopathologically the lesion comprised entirely fibrotic tissue consisting of thick collagenous fibers and sclerosing blood vessels with a few intervening viable cells with, partly, the immunophenotype of arachnoid cells. Intracranial fibrotic nodules are extremely rare. This tumor, however, had some radiological features similar to those of other, more common, tumors for example meningiomas or solitary fibrous tumors; it was, therefore, difficult to distinguish it from the others. It is believed that intracranial fibrotic nodules usually have benign, non-neoplastic characteristics, although their natural history is not yet fully understood. It is, therefore, necessary to be able to perform a differential diagnosis that will distinguish this rare condition from other intracranial fibrous neoplasms that occasionally have malignant features.
UR - http://www.scopus.com/inward/record.url?scp=84884722286&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84884722286&partnerID=8YFLogxK
U2 - 10.1007/s10014-012-0105-1
DO - 10.1007/s10014-012-0105-1
M3 - Article
C2 - 22678097
AN - SCOPUS:84884722286
VL - 30
SP - 122
EP - 127
JO - Brain Tumor Pathology
JF - Brain Tumor Pathology
SN - 1433-7398
IS - 2
ER -