TY - JOUR
T1 - A glucosylceramide with antimicrobial activity from the edible mushroom Pleurotus citrinopileatus
AU - Meng, Tian Xiao
AU - Ishikawa, Hiroya
AU - Shimizu, Kuniyoshi
AU - Ohga, Shoji
AU - Kondo, Ryuichiro
PY - 2012/2
Y1 - 2012/2
N2 - The golden oyster mushroom Pleurotus citrinopileatus is a popular edible mushroom with multifunctional biological activities, but there are a limited number of previous studies on its chemical composition. This is the first report of the isolation of glucosylceramide with antimicrobial activity from the fruiting body of this mushroom. This compound was identified as 1-O-β-D-glucopyranosyl-(2S,3R,4E,8E)-2-[(2R)-2-hydroxyhexadecanoylamino]-9-methyl-4,8-octadecadiene-1,3-diol. The IC 50 value of this compound for the growth of Escherichia coli and Staphylococcus aureus was 275. 1 μM (200 μg/ml) and 323. 2 μM (235 μg/ml), respectively.
AB - The golden oyster mushroom Pleurotus citrinopileatus is a popular edible mushroom with multifunctional biological activities, but there are a limited number of previous studies on its chemical composition. This is the first report of the isolation of glucosylceramide with antimicrobial activity from the fruiting body of this mushroom. This compound was identified as 1-O-β-D-glucopyranosyl-(2S,3R,4E,8E)-2-[(2R)-2-hydroxyhexadecanoylamino]-9-methyl-4,8-octadecadiene-1,3-diol. The IC 50 value of this compound for the growth of Escherichia coli and Staphylococcus aureus was 275. 1 μM (200 μg/ml) and 323. 2 μM (235 μg/ml), respectively.
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U2 - 10.1007/s10086-011-1213-y
DO - 10.1007/s10086-011-1213-y
M3 - Article
AN - SCOPUS:84857372081
SN - 1435-0211
VL - 58
SP - 81
EP - 86
JO - Journal of Wood Science
JF - Journal of Wood Science
IS - 1
ER -