A microfluidic analytical system, which uses simple technique to pick reacting DNA molecules out of a crowd of molecules during enzymatic reaction, was developed on the basis of single-molecule imaging. Restriction enzymes EcoR I and Not I with their target and non-target DNA were analyzed. With this system, we measured the duration difference of restriction-site-searching by these enzymes at the single-molecule level.
|出版ステータス||出版済み - 2008|
|イベント||12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, 米国|
継続期間: 10 12 2008 → 10 16 2008
|その他||12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008|
|City||San Diego, CA|
|Period||10/12/08 → 10/16/08|
All Science Journal Classification (ASJC) codes