A multi-step, incremental expansion method for radio frequency ablation: Optimization of the procedure to prevent increases in intra-tumor pressure and to reduce the ablation time

Kazuhiro Kotoh, Makoto Nakamuta, Shusuke Morizono, Motoyuki Kohjima, Eiichirou Arimura, Marie Fukushima, Munechika Enjoji, Hironori Sakai, Hajime Nawata

研究成果: ジャーナルへの寄稿記事

39 引用 (Scopus)

抄録

Background/Aims: Radio frequency ablation (RFA) has been accepted clinically as a useful local treatment for hepatocellular carcinoma (HCC). However, intra-hepatic recurrence after RFA has been reported. We initially hypothesized that recurrence was attributable to increases in intratumor pressure during RFA, and we subsequently measured the pressure and optimized the procedure. Methods: A block of pig liver sealed in a rigid plastic case was used as a model of an HCC tumor with a capsule. We compared the pressure between a single-step full expansion of the needle (single-step method) and incremental, stepwise expansion (multi-step method), and evaluated the effect of varying the electrical power. Finally, we performed a preliminary comparison of the ablation times for these methods in HCC cases. Results: The multi-step method resulted in a significantly lower pressure and shorter total ablation time than the single-step method. Furthermore, incremental expansion in 10 steps resulted in a lower pressure and shorter ablation time than four steps. Seventy W-ablation resulted in a lower pressure and shorter time than 30- or 50 W-ablation. In HCC cases, the multiple-step method had a significantly shorter ablation time than the single-step method. Conclusion: The multi-step method can be recommended to reduce the ablation time, and suppress the increase in pressure.

元の言語英語
ページ(範囲)542-547
ページ数6
ジャーナルLiver International
25
発行部数3
DOI
出版物ステータス出版済み - 6 1 2005

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Radio
Pressure
Neoplasms
Hepatocellular Carcinoma
Recurrence
Liver
Plastics
Capsules
Needles
Swine

All Science Journal Classification (ASJC) codes

  • Hepatology

これを引用

A multi-step, incremental expansion method for radio frequency ablation : Optimization of the procedure to prevent increases in intra-tumor pressure and to reduce the ablation time. / Kotoh, Kazuhiro; Nakamuta, Makoto; Morizono, Shusuke; Kohjima, Motoyuki; Arimura, Eiichirou; Fukushima, Marie; Enjoji, Munechika; Sakai, Hironori; Nawata, Hajime.

:: Liver International, 巻 25, 番号 3, 01.06.2005, p. 542-547.

研究成果: ジャーナルへの寄稿記事

Kotoh, Kazuhiro ; Nakamuta, Makoto ; Morizono, Shusuke ; Kohjima, Motoyuki ; Arimura, Eiichirou ; Fukushima, Marie ; Enjoji, Munechika ; Sakai, Hironori ; Nawata, Hajime. / A multi-step, incremental expansion method for radio frequency ablation : Optimization of the procedure to prevent increases in intra-tumor pressure and to reduce the ablation time. :: Liver International. 2005 ; 巻 25, 番号 3. pp. 542-547.
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AU - Morizono, Shusuke

AU - Kohjima, Motoyuki

AU - Arimura, Eiichirou

AU - Fukushima, Marie

AU - Enjoji, Munechika

AU - Sakai, Hironori

AU - Nawata, Hajime

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