A new application of a peptide library to identify selective interaction between small peptides in an attempt to develop recognition molecules toward protein surfaces

Shigeki Sasaki, Manabu Takagi, Yoshitsugu Tanaka, Minoru Maeda

研究成果: Contribution to journalArticle査読

22 被引用数 (Scopus)

抄録

Combinatorial technologies with the use of a solid-phase pentapeptide library and the magnetic beads covalently bound with the target nonapeptide (1) were applied to search for recognition peptides toward the target sequence (1) which constitutes an extracellular part of the dopamine D2 receptor. Several pentapeptides have been identified to exhibit high binding affinities toward the target peptide (1) in an aqueous solution.

本文言語英語
ページ(範囲)85-88
ページ数4
ジャーナルTetrahedron Letters
37
1
DOI
出版ステータス出版済み - 1 1 1996

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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