A novel fiber-free technique for brain activity imaging in multiple freely behaving mice

Shigenori Inagaki, Masakazu Agetsuma, Takeharu Nagai

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

抄録

Brain functions and related psychiatric disorders have been investigated by recording electrophysiological field potential. When recording it, a conventional method requires fiber-based apparatus connected to the brain, which however hampers the simultaneous measurement in multiple animals (e.g. by a tangle of fibers). Here, we propose a fiber-free recording technique in conjunction with a ratiometric bioluminescent voltage indicator. Our method allows investigation of electrophysiological filed potential dynamics in multiple freely behaving animals simultaneously over a long time period. Therefore, this fiber-free technique opens up the way to investigate a new mechanism of brain function that governs social behaviors and animal-to-animal interaction.

本文言語英語
ホスト出版物のタイトルOptogenetics and Optical Manipulation 2018
編集者E. Duco Jansen, Samarendra K. Mohanty, Nitish V. Thakor, Nitish V. Thakor
出版社SPIE
ISBN(電子版)9781510614499
DOI
出版ステータス出版済み - 2018
外部発表はい
イベントOptogenetics and Optical Manipulation 2018 - San Francisco, 米国
継続期間: 1 27 20181 28 2018

出版物シリーズ

名前Progress in Biomedical Optics and Imaging - Proceedings of SPIE
10482
ISSN(印刷版)1605-7422

会議

会議Optogenetics and Optical Manipulation 2018
国/地域米国
CitySan Francisco
Period1/27/181/28/18

All Science Journal Classification (ASJC) codes

  • 電子材料、光学材料、および磁性材料
  • 生体材料
  • 原子分子物理学および光学
  • 放射線学、核医学およびイメージング

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