A novel hindered macrocyclic tetramine containing two bispidine units. A new type of proton sponge

Yuji Miyahara, Kenta Goto, Takahiko Inazu

研究成果: Contribution to journalArticle査読

30 被引用数 (Scopus)

抄録

A novel cyclam-like macrocyclic tetramine 1a was synthesized via coupling of bispidine and its bis(α-chloroacetamide) followed by reduction. Strongly basic but encrypted nitrogens of 1a were found to abstract a proton from chloroform to form dichlorocarbene.

本文言語英語
ページ(範囲)3097-3099
ページ数3
ジャーナルTetrahedron Letters
42
17
DOI
出版ステータス出版済み - 4 23 2001

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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