A nuclear factor which interacts with an at-cluster in the first intron of rat α2-macroglobulin gene

Takashi Ito, Yoshiyuki Sakaki

研究成果: Contribution to journalArticle査読

3 被引用数 (Scopus)

抄録

We have identified a nuclear protein which binds specifically to the first intron of rat α2-macroglobulin gene. The protein became insoluble at low salt concentration retaining the binding specificity. Its molecular weight was estimated to be 22 kilodalton by a protein blotting procedure. The binding site of the protein determined by DNase I footprinting was an AT-strech which shared 80% homology with the cleavage consensus of Drosophila topoisomerase II.

本文言語英語
ページ(範囲)824-830
ページ数7
ジャーナルBiochemical and Biophysical Research Communications
147
2
DOI
出版ステータス出版済み - 9 15 1987

All Science Journal Classification (ASJC) codes

  • 生物理学
  • 生化学
  • 分子生物学
  • 細胞生物学

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