A porphyrin tetramer for a positive homotropic allosteric recognition system: Efficient binding information transduction through butadiynyl axis rotation

Yohei Kubo, Masato Ikeda, Atsushi Sugasaki, Masayuki Takeuchi, Seiji Shinkai

研究成果: Contribution to journalArticle査読

25 被引用数 (Scopus)

抄録

A porphyrin tetramer 1 was newly designed and synthesized to construct a novel allosteric guest-binding system. Compound 1 has a butadiynyl rotational axis, which is expected to act as a guest-binding information transducer. In chloroform, 1 can bind bidentate amines, such as 1,3-di(4-piperidyl)propane (DPP), in an allosteric manner to produce a 1:2 1/diamine complex with a Hill coefficient of 1.9.

本文言語英語
ページ(範囲)7435-7438
ページ数4
ジャーナルTetrahedron Letters
42
42
DOI
出版ステータス出版済み - 10 15 2001

All Science Journal Classification (ASJC) codes

  • 生化学
  • 創薬
  • 有機化学

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