A possible maternal-effect mutant of Xenopus laevis: II. Studies of RNA synthesis in dissociated embryonic cells

Koichiro Shiokawa, Kosuke Tashiro, Norihiko Nakakura, Yuchang Fu, Yasuo Atsuchi, Sakiko Nakazato, Yoshinari Tsuzaki, Kohji Ikenishi

研究成果: Contribution to journalArticle査読

3 被引用数 (Scopus)

抄録

Embryos from a female of Xenopus laevis (designated as no. 65) arrest development at gastrulation and are assumed to be ova-deficient mutant. We dissociated these embryos and studied RNA synthesis at different stages. The cells from the ova-deficient embryos reaggregated quite actively as wild-type embryo cells until the late gastrula stage. RNA synthesis was normal at the early blastula stage but greatly inhibited by the late blastula (stage 9.5) stage, when the synthesis of DNA and protein was still not inhibited appreciably. Thus, inhibition in RNA synthesis appears to be the first manifestation of the maternal defect that occurs before the gastrulation arrest.

本文言語英語
ページ(範囲)47-55
ページ数9
ジャーナルCell Differentiation and Development
25
1
DOI
出版ステータス出版済み - 9 1988

All Science Journal Classification (ASJC) codes

  • 発生生物学

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