A preliminary study of the effect of DBD plasma and osmolytes on T98G brain cancer and HEK non-malignant cells

Nagendra Kumar Kaushik, Pankaj Attri, Neha Kaushik, Eun Ha Choi

研究成果: Contribution to journalArticle査読

41 被引用数 (Scopus)

抄録

Non-thermal plasmas are emerging as a novel tool for the treatment of living tissues for biological and medical purpose. In this study, we described the effect of 4 min dielectric barrier discharge (DBD) plasma on both T98G cancer and HEK normal cell lines in the presence of different concentrations of osmolytes. This treatment strategy shows a specific inhibitory effect of a 240 s plasma exposure in the presence of osmolytes against T98G brain cancer cells only, but not on HEK normal cells. Based on these interesting properties of osmolytes, a non-thermal plasma appears to be a potential anticancer treatment strategy for different kinds of cancers in the presence of osmolytes.

本文言語英語
ページ(範囲)4917-4928
ページ数12
ジャーナルMolecules
18
5
DOI
出版ステータス出版済み - 5 2013
外部発表はい

All Science Journal Classification (ASJC) codes

  • 分析化学
  • 化学(その他)
  • 分子医療
  • 薬科学
  • 創薬
  • 物理化学および理論化学
  • 有機化学

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