A pro-con debate: Current controversies in pah pathogenesis at the american thoracic society international conference in 2017

Wolfgang M. Kuebler, Mark R. Nicolls, Andrea Olschewski, Kohtaro Abe, Marlene Rabinovitch, Duncan Stewart, Stephen Y. Chan, Nicholas W. Morrell, Stephen L. Archer, Edda Spiekerkoetter

研究成果: Contribution to journalReview article査読

6 被引用数 (Scopus)

抄録

The following review summarizes the pro-con debate about current controversies regarding the pathogenesis of pulmonary arterial hypertension (PAH) that took place at the American Thoracic Society Conference in May 2017. Leaders in the field of PAH research discussed the importance of the immune system, the role of hemodynamic stress and endothelial apoptosis, as well as bone morphogenetic protein receptor-2 signaling in PAH pathogenesis. Whereas this summary does not intend to resolve obvious conflicts in opinion, we hope that the presented arguments entice further discussions and draw a new generation of enthusiastic researchers into this vibrant field of science to bridge existing gaps for a better understanding and therapy of this fatal disease.

本文言語英語
ページ(範囲)L502-L516
ジャーナルAmerican Journal of Physiology - Lung Cellular and Molecular Physiology
315
4
DOI
出版ステータス出版済み - 10 2018

All Science Journal Classification (ASJC) codes

  • 生理学
  • 呼吸器内科
  • 生理学(医学)
  • 細胞生物学

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