A simple, general, and highly chemoselective acetylation of alcohols using ethyl acetate as the acetyl donor catalyzed by a tetranuclear zinc cluster

Takanori Iwasaki, Yusuke Maegawa, Yukiko Hayashi, Takashi Ohshima, Kazushi Mashima

研究成果: Contribution to journalArticle査読

31 被引用数 (Scopus)

抄録

In the presence of a Zn-cluster catalyst, alcohols are efficiently converted to the corresponding acetate just by refluxing in EtOAc. The mild reaction conditions enabled the reactions of various functionalized alcohols to proceed in good to excellent yield. Moreover, even when a large excess of the acetyl donor is used, the hydroxyl groups are selectively acetylated in the presence of highly nucleophilic aliphatic amino groups, approaching chemoselectivity to that of enzymatic system.

本文言語英語
ページ(範囲)1659-1663
ページ数5
ジャーナルSynlett
10
DOI
出版ステータス出版済み - 6 2009
外部発表はい

All Science Journal Classification (ASJC) codes

  • 有機化学

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