A trans-chelating bisphosphine possessing only planar chirality and its application to catalytic asymmetric reactions

Ryoichi Kuwano, Takashi Uemura, Makoto Saitoh, Yoshihiko Ito

研究成果: Contribution to journalArticle査読

40 被引用数 (Scopus)

抄録

A new chiral bisphosphine, (S,S)-2,2″-bis[(diethylphosphino)methyl]- 1,1″-biferrocene [(S,S)-EtTRAP-H], was synthesized in seven steps in 45% overall yield from ferrocenyloxazoline derived from (S)-valinol. The new chiral phosphine has only planar chirality, and is able to form a trans-chelate metal complex. (S,S)-EtTRAP-H is an effective ligand in rhodium-catalyzed asymmetric hydrosilylation of ketones (up to 94% ee). In particular, the hydrosilylation of 2-octanone yielded (S)-2-octanol with 77% ee.

本文言語英語
ページ(範囲)2263-2271
ページ数9
ジャーナルTetrahedron Asymmetry
15
14
DOI
出版ステータス出版済み - 7 26 2004

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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