Aaptamine-related alkaloid from the marine sponge aaptos aaptos

Toshiyuki Hamada, Yoshito Matsumoto, Chin Soon Phan, Takashi Kamada, Satoaki Onitsuka, Hiroaki Okamura, Tetsuo Iwagawa, Naomichi Arima, Fumito Tani, Charles S. Vairappan

研究成果: Contribution to journalArticle

3 引用 (Scopus)

抜粋

A new aaptamine-related alkaloid, 1,3-dioxolo [4,5-d] benzo [de]-1,6-naphthyridine (methylenedioxyaaptamine, 1), was isolated from the organic extracts of the Bornean marine sponge Aaptos aaptos, together with a known aaptamine derivative, 8,9,9-trime-thoxy-9H-benzo [de]-1,6-naphthyridine (2). The structure of compound 1 was elucidated by interpretation of its spectroscopic data. Two compounds were tested for their cytotoxic potentials against adult T-cell leukemia (ATL) cells, and compound 1 showed moderate cytotoxic potential.

元の言語英語
ページ(範囲)1-3
ページ数3
ジャーナルNatural product communications
14
発行部数9
DOI
出版物ステータス出版済み - 1 1 2019

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Plant Science
  • Drug Discovery
  • Complementary and alternative medicine

フィンガープリント Aaptamine-related alkaloid from the marine sponge aaptos aaptos' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用

    Hamada, T., Matsumoto, Y., Phan, C. S., Kamada, T., Onitsuka, S., Okamura, H., Iwagawa, T., Arima, N., Tani, F., & Vairappan, C. S. (2019). Aaptamine-related alkaloid from the marine sponge aaptos aaptos. Natural product communications, 14(9), 1-3. https://doi.org/10.1177/1934578X19863935