Aaptamine-related alkaloid from the marine sponge aaptos aaptos

Toshiyuki Hamada, Yoshito Matsumoto, Chin Soon Phan, Takashi Kamada, Satoaki Onitsuka, Hiroaki Okamura, Tetsuo Iwagawa, Naomichi Arima, Fumito Tani, Charles S. Vairappan

研究成果: ジャーナルへの寄稿記事

抄録

A new aaptamine-related alkaloid, 1,3-dioxolo [4,5-d] benzo [de]-1,6-naphthyridine (methylenedioxyaaptamine, 1), was isolated from the organic extracts of the Bornean marine sponge Aaptos aaptos, together with a known aaptamine derivative, 8,9,9-trime-thoxy-9H-benzo [de]-1,6-naphthyridine (2). The structure of compound 1 was elucidated by interpretation of its spectroscopic data. Two compounds were tested for their cytotoxic potentials against adult T-cell leukemia (ATL) cells, and compound 1 showed moderate cytotoxic potential.

元の言語英語
ページ(範囲)1-3
ページ数3
ジャーナルNatural product communications
14
発行部数9
DOI
出版物ステータス出版済み - 1 1 2019

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Aaptos aaptos
Naphthyridines
Porifera
leukemia
Alkaloids
alkaloids
T-lymphocytes
chemical derivatives
Adult T Cell Leukemia Lymphoma
extracts
cells
aaptamine

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Plant Science
  • Drug Discovery
  • Complementary and alternative medicine

これを引用

Hamada, T., Matsumoto, Y., Phan, C. S., Kamada, T., Onitsuka, S., Okamura, H., ... Vairappan, C. S. (2019). Aaptamine-related alkaloid from the marine sponge aaptos aaptos. Natural product communications, 14(9), 1-3. https://doi.org/10.1177/1934578X19863935

Aaptamine-related alkaloid from the marine sponge aaptos aaptos. / Hamada, Toshiyuki; Matsumoto, Yoshito; Phan, Chin Soon; Kamada, Takashi; Onitsuka, Satoaki; Okamura, Hiroaki; Iwagawa, Tetsuo; Arima, Naomichi; Tani, Fumito; Vairappan, Charles S.

:: Natural product communications, 巻 14, 番号 9, 01.01.2019, p. 1-3.

研究成果: ジャーナルへの寄稿記事

Hamada, T, Matsumoto, Y, Phan, CS, Kamada, T, Onitsuka, S, Okamura, H, Iwagawa, T, Arima, N, Tani, F & Vairappan, CS 2019, 'Aaptamine-related alkaloid from the marine sponge aaptos aaptos', Natural product communications, 巻. 14, 番号 9, pp. 1-3. https://doi.org/10.1177/1934578X19863935
Hamada T, Matsumoto Y, Phan CS, Kamada T, Onitsuka S, Okamura H その他. Aaptamine-related alkaloid from the marine sponge aaptos aaptos. Natural product communications. 2019 1 1;14(9):1-3. https://doi.org/10.1177/1934578X19863935
Hamada, Toshiyuki ; Matsumoto, Yoshito ; Phan, Chin Soon ; Kamada, Takashi ; Onitsuka, Satoaki ; Okamura, Hiroaki ; Iwagawa, Tetsuo ; Arima, Naomichi ; Tani, Fumito ; Vairappan, Charles S. / Aaptamine-related alkaloid from the marine sponge aaptos aaptos. :: Natural product communications. 2019 ; 巻 14, 番号 9. pp. 1-3.
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AU - Okamura, Hiroaki

AU - Iwagawa, Tetsuo

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