Acquired hemophilia in a patient with systemic lupus erythematosus: A case report and literature review

Mitsuteru Akahoshi, Kumiko Aizawa, Shuji Nagano, Hisako Inoue, Atsushi Sadanaga, Yojiro Arinobu, Hiroaki Niiro, Hitoshi Nakashima

研究成果: ジャーナルへの寄稿記事

13 引用 (Scopus)

抄録

We report the case of a 38-year-old female patient with systemic lupus erythematosus (SLE) who developed acquired hemophilia caused by factor VIII (FVIII) inhibitors. She manifested spontaneous bleeding symptoms such as ecchymoses and hematuria. Laboratory findings showed an isolated prolongation of the activated partial thromboplastin time, reduced FVIII activity, and a high titer of FVIII inhibitors. She was successfully treated with oral predonisolone and cyclosporine in combination with steroid and cyclophosphamide pulse therapy.

元の言語英語
ページ(範囲)511-515
ページ数5
ジャーナルModern Rheumatology
18
発行部数5
DOI
出版物ステータス出版済み - 6 13 2008

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Factor VIII
Hemophilia A
Systemic Lupus Erythematosus
Ecchymosis
Partial Thromboplastin Time
Hematuria
Cyclophosphamide
Cyclosporine
Steroids
Hemorrhage
Therapeutics

All Science Journal Classification (ASJC) codes

  • Rheumatology

これを引用

Acquired hemophilia in a patient with systemic lupus erythematosus : A case report and literature review. / Akahoshi, Mitsuteru; Aizawa, Kumiko; Nagano, Shuji; Inoue, Hisako; Sadanaga, Atsushi; Arinobu, Yojiro; Niiro, Hiroaki; Nakashima, Hitoshi.

:: Modern Rheumatology, 巻 18, 番号 5, 13.06.2008, p. 511-515.

研究成果: ジャーナルへの寄稿記事

Akahoshi, Mitsuteru ; Aizawa, Kumiko ; Nagano, Shuji ; Inoue, Hisako ; Sadanaga, Atsushi ; Arinobu, Yojiro ; Niiro, Hiroaki ; Nakashima, Hitoshi. / Acquired hemophilia in a patient with systemic lupus erythematosus : A case report and literature review. :: Modern Rheumatology. 2008 ; 巻 18, 番号 5. pp. 511-515.
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AU - Niiro, Hiroaki

AU - Nakashima, Hitoshi

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AB - We report the case of a 38-year-old female patient with systemic lupus erythematosus (SLE) who developed acquired hemophilia caused by factor VIII (FVIII) inhibitors. She manifested spontaneous bleeding symptoms such as ecchymoses and hematuria. Laboratory findings showed an isolated prolongation of the activated partial thromboplastin time, reduced FVIII activity, and a high titer of FVIII inhibitors. She was successfully treated with oral predonisolone and cyclosporine in combination with steroid and cyclophosphamide pulse therapy.

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