Acrylic scaffolds with interconnected spherical pores and controlled hydrophilicity for tissue engineering

R. Brígido Diego, M. Pérez Olmedilla, A. Serrano Aroca, J. L. Gómez Ribelles, M. Monleón Pradas, G. Gallego Ferrer, M. Salmerón Sánchez

研究成果: Contribution to journalArticle査読

39 被引用数 (Scopus)

抄録

Polymer scaffolds are obtained in which the geometric characteristics (pore size, connectivity, porosity) and the physico-chemical properties of the resulting material can be controlled in an independent way. The interconnected porous structure was obtained using a template of sintered PMMA microspheres of controlled size. Copolymerization of hydrophobic ethyl acrylate and hydrophilic hydroxyethyl methacrylate comonomers took place in the free space of the template, different comonomer ratio gave rise to different hydrophilicity degrees of the material keeping the same pore architecture. The morphology of the resulting scaffolds was investigated by scanning electron microscopy (SEM), the porosity of the material calculated, and the mechanical properties compared with those of the bulk (non porous) material of the same composition.

本文言語英語
ページ(範囲)693-698
ページ数6
ジャーナルJournal of Materials Science: Materials in Medicine
16
8
DOI
出版ステータス出版済み - 8 2005
外部発表はい

All Science Journal Classification (ASJC) codes

  • 生物理学
  • バイオエンジニアリング
  • 生体材料
  • 生体医工学

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