TY - JOUR
T1 - Acrylic scaffolds with interconnected spherical pores and controlled hydrophilicity for tissue engineering
AU - Brígido Diego, R.
AU - Pérez Olmedilla, M.
AU - Serrano Aroca, A.
AU - Gómez Ribelles, J. L.
AU - Monleón Pradas, M.
AU - Gallego Ferrer, G.
AU - Salmerón Sánchez, M.
N1 - Funding Information:
This work was supported by the Spanish Science and Technology Ministry through the MAT2001-2678-C02-01 and MAT 2002-04239-C03-03 projects. Support to the research group by the Genemlitat Valenciana, through the Groupos 03/018 is acknowledged.
PY - 2005/8
Y1 - 2005/8
N2 - Polymer scaffolds are obtained in which the geometric characteristics (pore size, connectivity, porosity) and the physico-chemical properties of the resulting material can be controlled in an independent way. The interconnected porous structure was obtained using a template of sintered PMMA microspheres of controlled size. Copolymerization of hydrophobic ethyl acrylate and hydrophilic hydroxyethyl methacrylate comonomers took place in the free space of the template, different comonomer ratio gave rise to different hydrophilicity degrees of the material keeping the same pore architecture. The morphology of the resulting scaffolds was investigated by scanning electron microscopy (SEM), the porosity of the material calculated, and the mechanical properties compared with those of the bulk (non porous) material of the same composition.
AB - Polymer scaffolds are obtained in which the geometric characteristics (pore size, connectivity, porosity) and the physico-chemical properties of the resulting material can be controlled in an independent way. The interconnected porous structure was obtained using a template of sintered PMMA microspheres of controlled size. Copolymerization of hydrophobic ethyl acrylate and hydrophilic hydroxyethyl methacrylate comonomers took place in the free space of the template, different comonomer ratio gave rise to different hydrophilicity degrees of the material keeping the same pore architecture. The morphology of the resulting scaffolds was investigated by scanning electron microscopy (SEM), the porosity of the material calculated, and the mechanical properties compared with those of the bulk (non porous) material of the same composition.
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U2 - 10.1007/s10856-005-2604-7
DO - 10.1007/s10856-005-2604-7
M3 - Article
C2 - 15965737
AN - SCOPUS:21344457900
VL - 16
SP - 693
EP - 698
JO - Journal of Materials Science: Materials in Electronics
JF - Journal of Materials Science: Materials in Electronics
SN - 0957-4522
IS - 8
ER -