Activation of p53-Mediated Apoptosis Pathway in HSC3 Cancer Cell Irradiated by Atmospheric DBD Oxygen Plasma

Nobuya Hayashi, Yukie Miyamaru, Reona Aijima, Yoshio Yamashita

研究成果: ジャーナルへの寄稿記事

抄録

Oral cancer cell HSC3 is inactivated by the direct irradiation of oxygen plasma generated by torch-type oxygen dielectric barrier discharge. Selective inactivation of the cancer cells is observed at the discharge voltage of 4.2 kV, where normal cells suffer no damages from the plasma. Inactivation mechanism of HSC3 cells irradiated by the plasma is considered as the apoptosis. Activation of mitogen-activated protein kinase and p53 proteins owing to the phosphorylation is one of the pathways to the cancer cell apoptosis.

元の言語英語
記事番号8464083
ページ(範囲)1093-1099
ページ数7
ジャーナルIEEE Transactions on Plasma Science
47
発行部数2
DOI
出版物ステータス出版済み - 2 1 2019

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oxygen plasma
apoptosis
cancer
activation
deactivation
proteins
phosphorylation
torches
damage
irradiation
electric potential
oxygen
cells

All Science Journal Classification (ASJC) codes

  • Nuclear and High Energy Physics
  • Condensed Matter Physics

これを引用

Activation of p53-Mediated Apoptosis Pathway in HSC3 Cancer Cell Irradiated by Atmospheric DBD Oxygen Plasma. / Hayashi, Nobuya; Miyamaru, Yukie; Aijima, Reona; Yamashita, Yoshio.

:: IEEE Transactions on Plasma Science, 巻 47, 番号 2, 8464083, 01.02.2019, p. 1093-1099.

研究成果: ジャーナルへの寄稿記事

Hayashi, Nobuya ; Miyamaru, Yukie ; Aijima, Reona ; Yamashita, Yoshio. / Activation of p53-Mediated Apoptosis Pathway in HSC3 Cancer Cell Irradiated by Atmospheric DBD Oxygen Plasma. :: IEEE Transactions on Plasma Science. 2019 ; 巻 47, 番号 2. pp. 1093-1099.
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