Acute effects of triclosan, diclofenac and carbamazepine on feeding performance of Japanese medaka fish (Oryzias latipes)

Mohamed Nassef, Shuhei Matsumoto, Masanori Seki, Fatma Khalil, Ikjoon Kang, Yohei Shimasaki, Yuji Oshima, Tsuneo Honjo

研究成果: ジャーナルへの寄稿記事

106 引用 (Scopus)

抄録

The toxicity of three pharmaceutical and personal care products (PPCPs) - carbamazepine (CBMZ), diclofenac (DCF), and triclosan (TCS) - was examined by measuring their effects on feeding behavior and swimming speed of adult Japanese medaka fish (Oryzias latipes). Medaka were exposed to 6.15mgL -1 CBMZ, 1.0mgL -1 DCF, 0.17mgL -1 TCS, or no PPCP (control) for 9d. Fish behaviors were monitored during days 5-9 of the exposure period. Feeding behavior (time to eat midge larvae, TE) and swimming speed (SS) of individual exposed and control fish were tracked in two dimensions, using an automated system with a digital charge-coupled device camera. As a result, feeding behavior was affected by exposure to CBMZ and DCF, while SS was altered by exposure to CBMZ and TCS. Thus, TCS, DCF and CBMZ appear to affect fish behaviors through different mechanisms. Overall, the results suggest that behavioral changes may provide a sensitive indicator for assessing the toxicity of PPCPs to aquatic organisms.

元の言語英語
ページ(範囲)1095-1100
ページ数6
ジャーナルChemosphere
80
発行部数9
DOI
出版物ステータス出版済み - 8 1 2010

Fingerprint

Triclosan
Oryzias
Diclofenac
Carbamazepine
Fish
Fishes
feeding behavior
Pharmaceutical Services
Drug products
Feeding Behavior
fish
Toxicity
toxicity
Aquatic organisms
Pharmaceutical Preparations
Digital cameras
CCD cameras
aquatic organism
Aquatic Organisms
Larva

All Science Journal Classification (ASJC) codes

  • Environmental Chemistry
  • Chemistry(all)

これを引用

Acute effects of triclosan, diclofenac and carbamazepine on feeding performance of Japanese medaka fish (Oryzias latipes). / Nassef, Mohamed; Matsumoto, Shuhei; Seki, Masanori; Khalil, Fatma; Kang, Ikjoon; Shimasaki, Yohei; Oshima, Yuji; Honjo, Tsuneo.

:: Chemosphere, 巻 80, 番号 9, 01.08.2010, p. 1095-1100.

研究成果: ジャーナルへの寄稿記事

Nassef, Mohamed ; Matsumoto, Shuhei ; Seki, Masanori ; Khalil, Fatma ; Kang, Ikjoon ; Shimasaki, Yohei ; Oshima, Yuji ; Honjo, Tsuneo. / Acute effects of triclosan, diclofenac and carbamazepine on feeding performance of Japanese medaka fish (Oryzias latipes). :: Chemosphere. 2010 ; 巻 80, 番号 9. pp. 1095-1100.
@article{5f3c5d36c5cd4d00bf5332a67e637012,
title = "Acute effects of triclosan, diclofenac and carbamazepine on feeding performance of Japanese medaka fish (Oryzias latipes)",
abstract = "The toxicity of three pharmaceutical and personal care products (PPCPs) - carbamazepine (CBMZ), diclofenac (DCF), and triclosan (TCS) - was examined by measuring their effects on feeding behavior and swimming speed of adult Japanese medaka fish (Oryzias latipes). Medaka were exposed to 6.15mgL -1 CBMZ, 1.0mgL -1 DCF, 0.17mgL -1 TCS, or no PPCP (control) for 9d. Fish behaviors were monitored during days 5-9 of the exposure period. Feeding behavior (time to eat midge larvae, TE) and swimming speed (SS) of individual exposed and control fish were tracked in two dimensions, using an automated system with a digital charge-coupled device camera. As a result, feeding behavior was affected by exposure to CBMZ and DCF, while SS was altered by exposure to CBMZ and TCS. Thus, TCS, DCF and CBMZ appear to affect fish behaviors through different mechanisms. Overall, the results suggest that behavioral changes may provide a sensitive indicator for assessing the toxicity of PPCPs to aquatic organisms.",
author = "Mohamed Nassef and Shuhei Matsumoto and Masanori Seki and Fatma Khalil and Ikjoon Kang and Yohei Shimasaki and Yuji Oshima and Tsuneo Honjo",
year = "2010",
month = "8",
day = "1",
doi = "10.1016/j.chemosphere.2010.04.073",
language = "English",
volume = "80",
pages = "1095--1100",
journal = "Chemosphere",
issn = "0045-6535",
publisher = "Elsevier Limited",
number = "9",

}

TY - JOUR

T1 - Acute effects of triclosan, diclofenac and carbamazepine on feeding performance of Japanese medaka fish (Oryzias latipes)

AU - Nassef, Mohamed

AU - Matsumoto, Shuhei

AU - Seki, Masanori

AU - Khalil, Fatma

AU - Kang, Ikjoon

AU - Shimasaki, Yohei

AU - Oshima, Yuji

AU - Honjo, Tsuneo

PY - 2010/8/1

Y1 - 2010/8/1

N2 - The toxicity of three pharmaceutical and personal care products (PPCPs) - carbamazepine (CBMZ), diclofenac (DCF), and triclosan (TCS) - was examined by measuring their effects on feeding behavior and swimming speed of adult Japanese medaka fish (Oryzias latipes). Medaka were exposed to 6.15mgL -1 CBMZ, 1.0mgL -1 DCF, 0.17mgL -1 TCS, or no PPCP (control) for 9d. Fish behaviors were monitored during days 5-9 of the exposure period. Feeding behavior (time to eat midge larvae, TE) and swimming speed (SS) of individual exposed and control fish were tracked in two dimensions, using an automated system with a digital charge-coupled device camera. As a result, feeding behavior was affected by exposure to CBMZ and DCF, while SS was altered by exposure to CBMZ and TCS. Thus, TCS, DCF and CBMZ appear to affect fish behaviors through different mechanisms. Overall, the results suggest that behavioral changes may provide a sensitive indicator for assessing the toxicity of PPCPs to aquatic organisms.

AB - The toxicity of three pharmaceutical and personal care products (PPCPs) - carbamazepine (CBMZ), diclofenac (DCF), and triclosan (TCS) - was examined by measuring their effects on feeding behavior and swimming speed of adult Japanese medaka fish (Oryzias latipes). Medaka were exposed to 6.15mgL -1 CBMZ, 1.0mgL -1 DCF, 0.17mgL -1 TCS, or no PPCP (control) for 9d. Fish behaviors were monitored during days 5-9 of the exposure period. Feeding behavior (time to eat midge larvae, TE) and swimming speed (SS) of individual exposed and control fish were tracked in two dimensions, using an automated system with a digital charge-coupled device camera. As a result, feeding behavior was affected by exposure to CBMZ and DCF, while SS was altered by exposure to CBMZ and TCS. Thus, TCS, DCF and CBMZ appear to affect fish behaviors through different mechanisms. Overall, the results suggest that behavioral changes may provide a sensitive indicator for assessing the toxicity of PPCPs to aquatic organisms.

UR - http://www.scopus.com/inward/record.url?scp=77955171102&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77955171102&partnerID=8YFLogxK

U2 - 10.1016/j.chemosphere.2010.04.073

DO - 10.1016/j.chemosphere.2010.04.073

M3 - Article

VL - 80

SP - 1095

EP - 1100

JO - Chemosphere

JF - Chemosphere

SN - 0045-6535

IS - 9

ER -