Addition reactions to alkynes catalyzed by ruthenium complexes

Makoto Tokunaga, Yasuo Wakatsuki

研究成果: Contribution to journalArticle査読

14 被引用数 (Scopus)

抄録

Additions to C-C multiple bonds are simple and the most efficient methods in organic synthesis in terms of atom utilization due to avoidance of stoichiometric amounts of by-products. The following catalytic C-C, C-O and C-N bond-constructions by direct additions of nucleophiles to alkynes catalyzed by ruthenium complexes have been developed. 1) Dimerization of terminal alkynes to 1,4-disubstituted butatriens which is an unusual tail-to-tail coupled product. 2) The first example of anti-Markovnikov hydration of terminal alkynes to aldehydes. 3) Intermolecular hydroamination of terminal alkynes with anilines to imines. Some of the reactions proceed in high yields under solvent-free, open-air conditions. Theoretical studies were also performed about transformation of η2-coordinated 1-alkynes to vinylidene complexes which plays important role in regioselectivity of the addition reactions.

本文言語英語
ページ(範囲)587-596
ページ数10
ジャーナルYuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
58
6
DOI
出版ステータス出版済み - 6 2000
外部発表はい

All Science Journal Classification (ASJC) codes

  • 有機化学

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