Adenocarcinoma of the esophagogastric junction in Japan

Manabu Yamamoto, Hideo Baba, Akinori Egashira, Eiji Oki, Masahiko Ikebe, Yoshihiro Kakeji, Yoshihiko Maehara

研究成果: Contribution to journalArticle査読

3 被引用数 (Scopus)

抄録

Background/Aims: The prognosis of adenocarcinoma of the esophagogastric junction is worse than that in adenocarcinoma of other parts of the stomach. In particular, the clinical features and prognosis of adenocarcinoma of the esophagogastric junction and the differences between Siewert's type II and III tumors in Japan were evaluated. Methodology: We analyzed one hundred and forty patients with adenocarcinoma of the esophagogastric junction including one patient with a type I tumor, sixty-seven patients with type II tumors, and seventy-two patients with type III tumors. Results: The prognosis of patients with type III tumors was poorer in comparison to that of type II tumors in adenocarcinoma of the esophagogastric junction (p<0.05). A significant difference was observed in the survival of patients with type III tumors between those with positive and negative lymph nodes (p<0.001). However, there was no such difference in patients with type II tumors. In a multivariate analysis, lymph node metastasis, age and the depth of tumor invasion were all found to be independent prognostic factors. Conclusions: The prognosis of patients with lymph node metastasis of type III adenocarcinoma of the esophagogastric junction was found to be extremely poor. An aggressive treatment after surgery may therefore be necessary to improve the survival of this population.

本文言語英語
ページ(範囲)103-107
ページ数5
ジャーナルHepato-gastroenterology
55
81
出版ステータス出版済み - 1 2008

All Science Journal Classification (ASJC) codes

  • 肝臓学
  • 消化器病学

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