Adipokines: Therapeutic targets for metabolic syndrome

Kunihisa Kobayashi, Toyoshi Inoguchi

研究成果: Contribution to journalReview article

59 引用 (Scopus)

抜粋

For a long time it has been known that obesity (adiposity) is linked to insulin resistance. Recently, many investigators have reported that adipocytes secrete a variety of bioactive molecules, termed adipokines (adipocytokines), including TNFα, IL-6, leptin, adiponectin, resistin and so on. These adipokines play pivotal roles in energy homeostasis by affecting insulin sensitivity, glucose and lipid metabolisms, food intake, the coagulation system and inflammation. This review provides a summary of these adipose tissue-secreting biomolecules and discusses their feasibilities as drug targets for the treatment of metabolic syndrome.

元の言語英語
ページ(範囲)525-529
ページ数5
ジャーナルCurrent Drug Targets
6
発行部数4
DOI
出版物ステータス出版済み - 6 2005

All Science Journal Classification (ASJC) codes

  • Molecular Medicine
  • Pharmacology
  • Drug Discovery
  • Clinical Biochemistry

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