抄録
Chronic active Epstein-Barr virus (EBV) infection, which is considered to be a childhood diseases, often develops into natural killer (NK) or T-cell lymphoma after recurrent infectious mononucleosis (IM)-like symptoms. We describe a 56-year-old woman who developed NK-cell lymphoma after 9 months of recurrent IM-like symptoms, The patient had an unusual anti-EBV antibody profile. Increased levels of EBV genome were detected in the liver and peripheral blood. Several chemotherapy regimens were ineffective, and the patent died of progression of lymphoma. Certain subtypes of NK-cell lymphoma showing a long-lasting prodrome related to chronic EBV infection may exist.
| 元の言語 | 英語 |
|---|---|
| ページ（範囲） | 471-474 |
| ページ数 | 4 |
| ジャーナル | Internal Medicine |
| 巻 | 48 |
| 発行部数 | 6 |
| DOI | |
| 出版物ステータス | 出版済み - 7 14 2009 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Internal Medicine
これを引用
Adult patient with Epstein-Barr virus (EBV)-associated lymphoproliferative disorder : Chronic active EBV infection or de novo extranodal natural killer (NK)/T-cell lymphoma, nasal type? / Ohtsuka, Rie; Abe, Yasunobu; Sada, Eriko; Kiyasu, Junichi; Ashikari, Akiyo; Shiratsuchi, Motoaki; Nishimura, Junji; Takayanagi, Ryoichi; Ohshima, Koichi.
：: Internal Medicine, 巻 48, 番号 6, 14.07.2009, p. 471-474.研究成果: ジャーナルへの寄稿 › 記事
}
TY - JOUR
T1 - Adult patient with Epstein-Barr virus (EBV)-associated lymphoproliferative disorder
T2 - Chronic active EBV infection or de novo extranodal natural killer (NK)/T-cell lymphoma, nasal type?
AU - Ohtsuka, Rie
AU - Abe, Yasunobu
AU - Sada, Eriko
AU - Kiyasu, Junichi
AU - Ashikari, Akiyo
AU - Shiratsuchi, Motoaki
AU - Nishimura, Junji
AU - Takayanagi, Ryoichi
AU - Ohshima, Koichi
PY - 2009/7/14
Y1 - 2009/7/14
N2 - Chronic active Epstein-Barr virus (EBV) infection, which is considered to be a childhood diseases, often develops into natural killer (NK) or T-cell lymphoma after recurrent infectious mononucleosis (IM)-like symptoms. We describe a 56-year-old woman who developed NK-cell lymphoma after 9 months of recurrent IM-like symptoms, The patient had an unusual anti-EBV antibody profile. Increased levels of EBV genome were detected in the liver and peripheral blood. Several chemotherapy regimens were ineffective, and the patent died of progression of lymphoma. Certain subtypes of NK-cell lymphoma showing a long-lasting prodrome related to chronic EBV infection may exist.
AB - Chronic active Epstein-Barr virus (EBV) infection, which is considered to be a childhood diseases, often develops into natural killer (NK) or T-cell lymphoma after recurrent infectious mononucleosis (IM)-like symptoms. We describe a 56-year-old woman who developed NK-cell lymphoma after 9 months of recurrent IM-like symptoms, The patient had an unusual anti-EBV antibody profile. Increased levels of EBV genome were detected in the liver and peripheral blood. Several chemotherapy regimens were ineffective, and the patent died of progression of lymphoma. Certain subtypes of NK-cell lymphoma showing a long-lasting prodrome related to chronic EBV infection may exist.
UR - http://www.scopus.com/inward/record.url?scp=67650066274&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=67650066274&partnerID=8YFLogxK
U2 - 10.2169/internalmedicine.48.1346
DO - 10.2169/internalmedicine.48.1346
M3 - Article
C2 - 19293549
AN - SCOPUS:67650066274
VL - 48
SP - 471
EP - 474
JO - Internal Medicine
JF - Internal Medicine
SN - 0918-2918
IS - 6
ER -