Adult patient with Epstein-Barr virus (EBV)-associated lymphoproliferative disorder: Chronic active EBV infection or de novo extranodal natural killer (NK)/T-cell lymphoma, nasal type?

Rie Ohtsuka, Yasunobu Abe, Eriko Sada, Junichi Kiyasu, Akiyo Ashikari, Motoaki Shiratsuchi, Junji Nishimura, Ryoichi Takayanagi, Koichi Ohshima

研究成果: ジャーナルへの寄稿記事

9 引用 (Scopus)

抄録

Chronic active Epstein-Barr virus (EBV) infection, which is considered to be a childhood diseases, often develops into natural killer (NK) or T-cell lymphoma after recurrent infectious mononucleosis (IM)-like symptoms. We describe a 56-year-old woman who developed NK-cell lymphoma after 9 months of recurrent IM-like symptoms, The patient had an unusual anti-EBV antibody profile. Increased levels of EBV genome were detected in the liver and peripheral blood. Several chemotherapy regimens were ineffective, and the patent died of progression of lymphoma. Certain subtypes of NK-cell lymphoma showing a long-lasting prodrome related to chronic EBV infection may exist.

元の言語英語
ページ(範囲)471-474
ページ数4
ジャーナルInternal Medicine
48
発行部数6
DOI
出版物ステータス出版済み - 7 14 2009

Fingerprint

Natural Killer T-Cells
Epstein-Barr Virus Infections
Lymphoproliferative Disorders
T-Cell Lymphoma
Human Herpesvirus 4
Nose
Lymphoma
Infectious Mononucleosis
Natural Killer Cells
Genome
Drug Therapy
Antibodies
Liver

All Science Journal Classification (ASJC) codes

  • Internal Medicine

これを引用

Adult patient with Epstein-Barr virus (EBV)-associated lymphoproliferative disorder : Chronic active EBV infection or de novo extranodal natural killer (NK)/T-cell lymphoma, nasal type? / Ohtsuka, Rie; Abe, Yasunobu; Sada, Eriko; Kiyasu, Junichi; Ashikari, Akiyo; Shiratsuchi, Motoaki; Nishimura, Junji; Takayanagi, Ryoichi; Ohshima, Koichi.

:: Internal Medicine, 巻 48, 番号 6, 14.07.2009, p. 471-474.

研究成果: ジャーナルへの寄稿記事

Ohtsuka, Rie ; Abe, Yasunobu ; Sada, Eriko ; Kiyasu, Junichi ; Ashikari, Akiyo ; Shiratsuchi, Motoaki ; Nishimura, Junji ; Takayanagi, Ryoichi ; Ohshima, Koichi. / Adult patient with Epstein-Barr virus (EBV)-associated lymphoproliferative disorder : Chronic active EBV infection or de novo extranodal natural killer (NK)/T-cell lymphoma, nasal type?. :: Internal Medicine. 2009 ; 巻 48, 番号 6. pp. 471-474.
@article{0bde81e4d1d642dea2dedf890dfc6854,
title = "Adult patient with Epstein-Barr virus (EBV)-associated lymphoproliferative disorder: Chronic active EBV infection or de novo extranodal natural killer (NK)/T-cell lymphoma, nasal type?",
abstract = "Chronic active Epstein-Barr virus (EBV) infection, which is considered to be a childhood diseases, often develops into natural killer (NK) or T-cell lymphoma after recurrent infectious mononucleosis (IM)-like symptoms. We describe a 56-year-old woman who developed NK-cell lymphoma after 9 months of recurrent IM-like symptoms, The patient had an unusual anti-EBV antibody profile. Increased levels of EBV genome were detected in the liver and peripheral blood. Several chemotherapy regimens were ineffective, and the patent died of progression of lymphoma. Certain subtypes of NK-cell lymphoma showing a long-lasting prodrome related to chronic EBV infection may exist.",
author = "Rie Ohtsuka and Yasunobu Abe and Eriko Sada and Junichi Kiyasu and Akiyo Ashikari and Motoaki Shiratsuchi and Junji Nishimura and Ryoichi Takayanagi and Koichi Ohshima",
year = "2009",
month = "7",
day = "14",
doi = "10.2169/internalmedicine.48.1346",
language = "English",
volume = "48",
pages = "471--474",
journal = "Internal Medicine",
issn = "0918-2918",
publisher = "Japanese Society of Internal Medicine",
number = "6",

}

TY - JOUR

T1 - Adult patient with Epstein-Barr virus (EBV)-associated lymphoproliferative disorder

T2 - Chronic active EBV infection or de novo extranodal natural killer (NK)/T-cell lymphoma, nasal type?

AU - Ohtsuka, Rie

AU - Abe, Yasunobu

AU - Sada, Eriko

AU - Kiyasu, Junichi

AU - Ashikari, Akiyo

AU - Shiratsuchi, Motoaki

AU - Nishimura, Junji

AU - Takayanagi, Ryoichi

AU - Ohshima, Koichi

PY - 2009/7/14

Y1 - 2009/7/14

N2 - Chronic active Epstein-Barr virus (EBV) infection, which is considered to be a childhood diseases, often develops into natural killer (NK) or T-cell lymphoma after recurrent infectious mononucleosis (IM)-like symptoms. We describe a 56-year-old woman who developed NK-cell lymphoma after 9 months of recurrent IM-like symptoms, The patient had an unusual anti-EBV antibody profile. Increased levels of EBV genome were detected in the liver and peripheral blood. Several chemotherapy regimens were ineffective, and the patent died of progression of lymphoma. Certain subtypes of NK-cell lymphoma showing a long-lasting prodrome related to chronic EBV infection may exist.

AB - Chronic active Epstein-Barr virus (EBV) infection, which is considered to be a childhood diseases, often develops into natural killer (NK) or T-cell lymphoma after recurrent infectious mononucleosis (IM)-like symptoms. We describe a 56-year-old woman who developed NK-cell lymphoma after 9 months of recurrent IM-like symptoms, The patient had an unusual anti-EBV antibody profile. Increased levels of EBV genome were detected in the liver and peripheral blood. Several chemotherapy regimens were ineffective, and the patent died of progression of lymphoma. Certain subtypes of NK-cell lymphoma showing a long-lasting prodrome related to chronic EBV infection may exist.

UR - http://www.scopus.com/inward/record.url?scp=67650066274&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=67650066274&partnerID=8YFLogxK

U2 - 10.2169/internalmedicine.48.1346

DO - 10.2169/internalmedicine.48.1346

M3 - Article

C2 - 19293549

AN - SCOPUS:67650066274

VL - 48

SP - 471

EP - 474

JO - Internal Medicine

JF - Internal Medicine

SN - 0918-2918

IS - 6

ER -