Adult patient with Epstein-Barr virus (EBV)-associated lymphoproliferative disorder: Chronic active EBV infection or de novo extranodal natural killer (NK)/T-cell lymphoma, nasal type?

Rie Ohtsuka, Yasunobu Abe, Eriko Sada, Junichi Kiyasu, Akiyo Ashikari, Motoaki Shiratsuchi, Junji Nishimura, Ryoichi Takayanagi, Koichi Ohshima

研究成果: Contribution to journalArticle査読

10 被引用数 (Scopus)

抄録

Chronic active Epstein-Barr virus (EBV) infection, which is considered to be a childhood diseases, often develops into natural killer (NK) or T-cell lymphoma after recurrent infectious mononucleosis (IM)-like symptoms. We describe a 56-year-old woman who developed NK-cell lymphoma after 9 months of recurrent IM-like symptoms, The patient had an unusual anti-EBV antibody profile. Increased levels of EBV genome were detected in the liver and peripheral blood. Several chemotherapy regimens were ineffective, and the patent died of progression of lymphoma. Certain subtypes of NK-cell lymphoma showing a long-lasting prodrome related to chronic EBV infection may exist.

本文言語英語
ページ(範囲)471-474
ページ数4
ジャーナルInternal Medicine
48
6
DOI
出版ステータス出版済み - 2009

All Science Journal Classification (ASJC) codes

  • 内科学

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