Adult patient with Epstein-Barr virus (EBV)-associated lymphoproliferative disorder: Chronic active EBV infection or de novo extranodal natural killer (NK)/T-cell lymphoma, nasal type?

Rie Ohtsuka; Yasunobu Abe; Eriko Sada; Junichi Kiyasu; Akiyo Ashikari; Motoaki Shiratsuchi; Junji Nishimura; Ryoichi Takayanagi; Koichi Ohshima

doi:10.2169/internalmedicine.48.1346

Adult patient with Epstein-Barr virus (EBV)-associated lymphoproliferative disorder: Chronic active EBV infection or de novo extranodal natural killer (NK)/T-cell lymphoma, nasal type?

Rie Ohtsuka, Yasunobu Abe, Eriko Sada, Junichi Kiyasu, Akiyo Ashikari, Motoaki Shiratsuchi, Junji Nishimura, Ryoichi Takayanagi, Koichi Ohshima

内分泌代謝・糖尿病内科

研究成果: Contribution to journal › Article › 査読

10 被引用数 (Scopus)

抄録

Chronic active Epstein-Barr virus (EBV) infection, which is considered to be a childhood diseases, often develops into natural killer (NK) or T-cell lymphoma after recurrent infectious mononucleosis (IM)-like symptoms. We describe a 56-year-old woman who developed NK-cell lymphoma after 9 months of recurrent IM-like symptoms, The patient had an unusual anti-EBV antibody profile. Increased levels of EBV genome were detected in the liver and peripheral blood. Several chemotherapy regimens were ineffective, and the patent died of progression of lymphoma. Certain subtypes of NK-cell lymphoma showing a long-lasting prodrome related to chronic EBV infection may exist.

本文言語	英語
ページ（範囲）	471-474
ページ数	4
ジャーナル	Internal Medicine
巻	48
号	6
DOI	https://doi.org/10.2169/internalmedicine.48.1346
出版ステータス	出版済み - 2009

All Science Journal Classification (ASJC) codes

内科学

文献へのアクセス

10.2169/internalmedicine.48.1346

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フィンガープリント

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引用スタイル

Ohtsuka, R., Abe, Y., Sada, E., Kiyasu, J., Ashikari, A., Shiratsuchi, M., Nishimura, J., Takayanagi, R., & Ohshima, K. (2009). Adult patient with Epstein-Barr virus (EBV)-associated lymphoproliferative disorder: Chronic active EBV infection or de novo extranodal natural killer (NK)/T-cell lymphoma, nasal type? Internal Medicine, 48(6), 471-474. https://doi.org/10.2169/internalmedicine.48.1346

Adult patient with Epstein-Barr virus (EBV)-associated lymphoproliferative disorder : Chronic active EBV infection or de novo extranodal natural killer (NK)/T-cell lymphoma, nasal type? / Ohtsuka, Rie; Abe, Yasunobu; Sada, Eriko; Kiyasu, Junichi; Ashikari, Akiyo; Shiratsuchi, Motoaki; Nishimura, Junji; Takayanagi, Ryoichi; Ohshima, Koichi.

In: Internal Medicine, Vol. 48, No. 6, 2009, p. 471-474.

研究成果: Contribution to journal › Article › 査読

Ohtsuka, R, Abe, Y, Sada, E, Kiyasu, J, Ashikari, A, Shiratsuchi, M, Nishimura, J, Takayanagi, R & Ohshima, K 2009, 'Adult patient with Epstein-Barr virus (EBV)-associated lymphoproliferative disorder: Chronic active EBV infection or de novo extranodal natural killer (NK)/T-cell lymphoma, nasal type?', Internal Medicine, vol. 48, no. 6, pp. 471-474. https://doi.org/10.2169/internalmedicine.48.1346

Ohtsuka, Rie ; Abe, Yasunobu ; Sada, Eriko ; Kiyasu, Junichi ; Ashikari, Akiyo ; Shiratsuchi, Motoaki ; Nishimura, Junji ; Takayanagi, Ryoichi ; Ohshima, Koichi. / Adult patient with Epstein-Barr virus (EBV)-associated lymphoproliferative disorder : Chronic active EBV infection or de novo extranodal natural killer (NK)/T-cell lymphoma, nasal type?. In: Internal Medicine. 2009 ; Vol. 48, No. 6. pp. 471-474.

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abstract = "Chronic active Epstein-Barr virus (EBV) infection, which is considered to be a childhood diseases, often develops into natural killer (NK) or T-cell lymphoma after recurrent infectious mononucleosis (IM)-like symptoms. We describe a 56-year-old woman who developed NK-cell lymphoma after 9 months of recurrent IM-like symptoms, The patient had an unusual anti-EBV antibody profile. Increased levels of EBV genome were detected in the liver and peripheral blood. Several chemotherapy regimens were ineffective, and the patent died of progression of lymphoma. Certain subtypes of NK-cell lymphoma showing a long-lasting prodrome related to chronic EBV infection may exist.",

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