Advantage of autologous blood transfusion in surgery for hepatocellular carcinoma

Yoshito Tomimaru, Hidetoshi Eguchi, Shigeru Marubashi, Hiroshi Wada, Shogo Kobayashi, Masahiro Tanemura, Koji Umeshita, Yuichiro Doki, Masaki Mori, Hiroaki Nagano

研究成果: Contribution to journalArticle

5 被引用数 (Scopus)

抄録

AIM: To evaluate the significance of autologous blood transfusion (AT) in reducing homologous blood transfusion (HT) in surgery for hepatocellular carcinoma (HCC). METHODS: The proportion of patients who received HT was compared between two groups determined by the time of AT introduction; period A (1991-1994, n = 93) and period B (1995-2000, n = 201). Multivariate logistic regression analysis was performed in order to identify independent significant predictors of the need for HT. We also investigated the impact of AT and HT on long-term postoperative outcome after curative surgery for HCC. RESULTS: The proportion of patients with HT was significantly lower in period B than period A (18.9% vs 60.2%, P < 0.0001). Multivariate logistic regression analysis identified AT administration as a significant independent predictor of the need for HT (P < 0.0001). Disease-free survival in patients with AT was comparable to that without any transfusion. Multivariate analysis identified HT administration as an independent significant factor for poorer disease-free survival (P = 0.0380). CONCLUSION: AT administration significantly decreased the need for H T. Considering the postoperative survival disadvantage of H T, AT administration could improve the long-term outcome of HCC patients.

本文言語英語
ページ(範囲)3709-3715
ページ数7
ジャーナルWorld Journal of Gastroenterology
17
32
DOI
出版ステータス出版済み - 8 28 2011

All Science Journal Classification (ASJC) codes

  • Gastroenterology

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