Ag+ labeling: A convenient new tool for the characterization of hydrogen-bonded supramolecular assemblies by MALDI-TOF mass spectrometry

Peter Timmerman, Katrina A. Jolliffe, Mercedes Crego Calama, Jean Luc Weidmann, Leonard J. Prins, Francesca Cardullo, Bianca H.M. Snellink-Ruël, Roel H. Fokkens, Nico M.M. Nibbering, Seiji Shinkai, David N. Reinhoudt

研究成果: ジャーナルへの寄稿記事

47 引用 (Scopus)

抄録

Herein we describe our results on the characterization of a wide variety of different hydrogen-bonded assemblies by means of a novel matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) technique with Ag+ labeling. The labeling technique with Ag+ ions is extremely mild and provides a nondestructive way to generate charged assemblies that can be detected by mass spectrometry. Up to now more than 25 different single (13·23), double (33·26), and tetrarosettes (43·212) have been successfully characterized by the use of this method. The success of the method entirely depends on the presence of a suitable binding site for the Ag+ ion. A variety of functionalities has been identified that provide strong binding sites for Ag+, either acting in a cooperative way (π-arene and π-alkene donor functionalities) or individually (cyano and crown ether functionalities). The method works well for assemblies with molecular weights between 2000 and 8000 Da, and most likely far beyond this limit.

元の言語英語
ページ(範囲)4104-4115
ページ数12
ジャーナルChemistry - A European Journal
6
発行部数22
DOI
出版物ステータス出版済み - 11 17 2000

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Labeling
Mass spectrometry
Hydrogen
Binding sites
Binding Sites
Ions
Crown Ethers
Crown ethers
Alkenes
Olefins
Ionization
Desorption
Molecular weight
Lasers

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)
  • Organic Chemistry

これを引用

Ag+ labeling : A convenient new tool for the characterization of hydrogen-bonded supramolecular assemblies by MALDI-TOF mass spectrometry. / Timmerman, Peter; Jolliffe, Katrina A.; Crego Calama, Mercedes; Weidmann, Jean Luc; Prins, Leonard J.; Cardullo, Francesca; Snellink-Ruël, Bianca H.M.; Fokkens, Roel H.; Nibbering, Nico M.M.; Shinkai, Seiji; Reinhoudt, David N.

:: Chemistry - A European Journal, 巻 6, 番号 22, 17.11.2000, p. 4104-4115.

研究成果: ジャーナルへの寄稿記事

Timmerman, P, Jolliffe, KA, Crego Calama, M, Weidmann, JL, Prins, LJ, Cardullo, F, Snellink-Ruël, BHM, Fokkens, RH, Nibbering, NMM, Shinkai, S & Reinhoudt, DN 2000, 'Ag+ labeling: A convenient new tool for the characterization of hydrogen-bonded supramolecular assemblies by MALDI-TOF mass spectrometry', Chemistry - A European Journal, 巻. 6, 番号 22, pp. 4104-4115. https://doi.org/10.1002/1521-3765(20001117)6:22<4104::AID-CHEM4104>3.0.CO;2-Q
Timmerman, Peter ; Jolliffe, Katrina A. ; Crego Calama, Mercedes ; Weidmann, Jean Luc ; Prins, Leonard J. ; Cardullo, Francesca ; Snellink-Ruël, Bianca H.M. ; Fokkens, Roel H. ; Nibbering, Nico M.M. ; Shinkai, Seiji ; Reinhoudt, David N. / Ag+ labeling : A convenient new tool for the characterization of hydrogen-bonded supramolecular assemblies by MALDI-TOF mass spectrometry. :: Chemistry - A European Journal. 2000 ; 巻 6, 番号 22. pp. 4104-4115.
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AU - Weidmann, Jean Luc

AU - Prins, Leonard J.

AU - Cardullo, Francesca

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AU - Fokkens, Roel H.

AU - Nibbering, Nico M.M.

AU - Shinkai, Seiji

AU - Reinhoudt, David N.

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