Aggressive angiomyxoma of the pelvis with a cellular nodule composed of tumor cells showing epithelioid features

Shogo Tajima, Kenichi Kohashi, Bo Fan, Wataru Doi, Ryosuke Kimura, Yoshihiro Tamura, Hirokazu Abe, Yoshinao Oda

研究成果: ジャーナルへの寄稿記事

抄録

A 49-year-old female presented with an aggressive pelvic angiomyxoma (AAM). The completely resected specimen revealed the usual myxedematous tumor with a nodule inside it. Histopathologically, the myxedematous area consisted of bland spindle-shaped cells in the background of blood vessels of varying calibers, and the nodule was composed of tumor cells with epithelioid features. In the nodule, cellularity was increased and nuclear enlargement was observed, but nuclear atypia was not significant and mitotic figures were scarce. Immunohistochemically, both components were positive for desim, αSMA, estrogen receptors, and progesterone receptors. However, they were negative for AE1/3, EMA, S100, CD34, HMB45, and Melan A. The MIB-labeling index was 5.8% in the nodule and 1ess than 1% outside it. The nodule was therefore considered a benign component of AAM. To the best of our knowledge, the presence of such a nodule in AAM has not been reported previously.

元の言語英語
記事番号5397
ページ(範囲)102-105
ページ数4
ジャーナルRare Tumors
6
発行部数3
DOI
出版物ステータス出版済み - 8 4 2014

Fingerprint

Epithelioid Cells
Myxoma
Pelvis
MART-1 Antigen
Neoplasms
Progesterone Receptors
Estrogen Receptors
Blood Vessels

All Science Journal Classification (ASJC) codes

  • Histology
  • Oncology

これを引用

Aggressive angiomyxoma of the pelvis with a cellular nodule composed of tumor cells showing epithelioid features. / Tajima, Shogo; Kohashi, Kenichi; Fan, Bo; Doi, Wataru; Kimura, Ryosuke; Tamura, Yoshihiro; Abe, Hirokazu; Oda, Yoshinao.

:: Rare Tumors, 巻 6, 番号 3, 5397, 04.08.2014, p. 102-105.

研究成果: ジャーナルへの寄稿記事

Tajima, Shogo ; Kohashi, Kenichi ; Fan, Bo ; Doi, Wataru ; Kimura, Ryosuke ; Tamura, Yoshihiro ; Abe, Hirokazu ; Oda, Yoshinao. / Aggressive angiomyxoma of the pelvis with a cellular nodule composed of tumor cells showing epithelioid features. :: Rare Tumors. 2014 ; 巻 6, 番号 3. pp. 102-105.
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abstract = "A 49-year-old female presented with an aggressive pelvic angiomyxoma (AAM). The completely resected specimen revealed the usual myxedematous tumor with a nodule inside it. Histopathologically, the myxedematous area consisted of bland spindle-shaped cells in the background of blood vessels of varying calibers, and the nodule was composed of tumor cells with epithelioid features. In the nodule, cellularity was increased and nuclear enlargement was observed, but nuclear atypia was not significant and mitotic figures were scarce. Immunohistochemically, both components were positive for desim, αSMA, estrogen receptors, and progesterone receptors. However, they were negative for AE1/3, EMA, S100, CD34, HMB45, and Melan A. The MIB-labeling index was 5.8{\%} in the nodule and 1ess than 1{\%} outside it. The nodule was therefore considered a benign component of AAM. To the best of our knowledge, the presence of such a nodule in AAM has not been reported previously.",
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AU - Kohashi, Kenichi

AU - Fan, Bo

AU - Doi, Wataru

AU - Kimura, Ryosuke

AU - Tamura, Yoshihiro

AU - Abe, Hirokazu

AU - Oda, Yoshinao

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