AlCl3-mediated aldol cyclocondensation of 1,6- and 1,7-diones to cyclopentene and cyclohexene derivatives

Yuji Miyahara, Yoshio Ito

研究成果: ジャーナルへの寄稿記事

8 引用 (Scopus)

抄録

Exactly 1/3 mol of AlCl3 is sufficient to cyclize 1 mol of 1,?-dibenzoylbutane (or pentane) to a cyclopentenone (or hexenone) derivative in high yield at room temperature in 40 min to several hours. This condensation is driven by removing elements of water as HCl and Al(OH)3, and the product enones are exclusively unconjugated, unlike the base-catalyzed condensations providing thermodynamically more stable conjugated enones.

元の言語英語
ページ(範囲)6801-6807
ページ数7
ジャーナルJournal of Organic Chemistry
79
発行部数15
DOI
出版物ステータス出版済み - 1 1 2014

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Cyclopentanes
Condensation
Derivatives
Water
Temperature
aluminum chloride
cyclohexene
3-hydroxybutanal
cyclopentenone
pentane

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

これを引用

AlCl3-mediated aldol cyclocondensation of 1,6- and 1,7-diones to cyclopentene and cyclohexene derivatives. / Miyahara, Yuji; Ito, Yoshio.

:: Journal of Organic Chemistry, 巻 79, 番号 15, 01.01.2014, p. 6801-6807.

研究成果: ジャーナルへの寄稿記事

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