Allantopyrone E, a rare α-pyrone metabolite from the mangrove derived fungus Aspergillus versicolor

Marwa Elsbaey, Chiaki Tanaka, Tomofumi Miyamoto

研究成果: ジャーナルへの寄稿学術誌査読

4 被引用数 (Scopus)

抄録

A new α-pyrone derivative, with a rare substitution pattern, was isolated from the solid rice media of the fungal endophyte Aspergillus versicolor associated with the fruit of the mangrove Avicennia marina. It was named allantopyrone E, after allantopyrones C and D. The aforementioned three are the only diaryl-substituted α-pyrones to be reported from nature. The unique structure was elucidated based on one- and two dimensional NMR data as well as high resolution mass spectroscopy. A biosynthetic scheme was proposed for the new compound. Furthermore, allantopyrone E showed cytotoxic effect on HeLa cells with IC50= 50.97 μM.

本文言語英語
ページ(範囲)760-764
ページ数5
ジャーナルNatural Product Research
36
3
DOI
出版ステータス出版済み - 2022

All Science Journal Classification (ASJC) codes

  • 分析化学
  • 生化学
  • 植物科学
  • 有機化学

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