Allogeneic haematopoietic cell transplantation for adult acute myeloid leukaemia in second remission: a retrospective study of the Adult Acute Myeloid Leukaemia Working Group of the Japan Society for Haematopoietic Cell Transplantation (JSHCT)

Takaaki Konuma, Masamitsu Yanada, Satoshi Yamasaki, Yachiyo Kuwatsuka, Takahiro Fukuda, Takeshi Kobayashi, Yukiyasu Ozawa, Naoyuki Uchida, Shuichi Ota, Takumi Hoshino, Satoshi Takahashi, Yoshinobu Kanda, Yasunori Ueda, Minoko Takanashi, Junya Kanda, Tatsuo Ichinohe, Yoshiko Atsuta, Shingo Yano

研究成果: Contribution to journalArticle査読

1 被引用数 (Scopus)

抄録

To evaluate the outcomes and prognostic factors following allogeneic haematopoietic cell transplantation (HCT) for adult acute myeloid leukaemia (AML) in second complete remission (CR2), we retrospectively analysed the Japanese registration data of 1080 adult AML patients in CR2 who had received allogeneic HCT. The probability of overall survival and the cumulative incidence of relapse at 3 years was 66% and 19%, respectively. In multivariate analysis, older age, poor cytogenetics and shorter duration of first complete remission were significantly associated with a higher overall mortality. Our data demonstrated the significant efficacy of allogeneic HCT for adult AML in CR2.

本文言語英語
ページ(範囲)245-250
ページ数6
ジャーナルBritish Journal of Haematology
182
2
DOI
出版ステータス出版済み - 7 2018
外部発表はい

All Science Journal Classification (ASJC) codes

  • 血液学

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