[Amebic colitis and liver abscess complicated by high serum procalcitonin in acute myeloid leukemia].

Eijiro Oku, Kei Nomura, Takayuki Nakamura, Satoshi Morishige, Ritsuko Seki, Rie Imamura, Michitoshi Hashiguchi, Kouichi Osaki, Shinichi Mizuno, Koji Nagafuji, Takashi Okamura

    研究成果: Contribution to journalArticle査読

    6 被引用数 (Scopus)

    抄録

    We present a case of amebic colitis and liver abscess complicated by acute myeloid leukemia (AML) with high serum procalcitonin (PCT). A 61-year-old Japanese man seen at our hospital for severe diarrhea and high fever was found to have multiple ulcers in the transverse and sigmoid colon and rectum by colonoscopy and biopsies were conducted. Immature leukocytes with mild anemia and thrombocytopenia were seen in peripheral blood, necessitating bone marrow aspiration and biopsy that yielded a diagnosis of AML (FAB M4Eo). Serum C-reactive protein and PCT were extremely elevated. Blood cultures for bacteria and fungi were negative. Multiple low-density areas in the liver were found in abdominal computed tomography. Histological colon biopsy findings revealed amebic colitis, strongly suggesting amebic liver abscess. Metronidazole treatment was initiated for amebiasis and subsequent standard chemotherapy for AML was followed after fever was lowered. Hematological and cytogenetic CR was maintained with good clinical condition. Few case reports have been published in Japan to date on amebic colitis and liver abscess complicated by AML and no reports have been made on PCT elevation caused by amebiasis. In conclusion, differential diagnosis of amebiasis is necessary in addition to that of bacterial or fungal infection in serum PCT elevation.

    本文言語英語
    ページ(範囲)773-777
    ページ数5
    ジャーナルUnknown Journal
    86
    6
    DOI
    出版ステータス出版済み - 11 2012

    All Science Journal Classification (ASJC) codes

    • Medicine(all)

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