An adenylyl cyclase, CyaB, acts as an osmosensor in Myxococcus xanthus

Yoshio Kimura, Mika Ohtani, Kaoru Takegawa

研究成果: ジャーナルへの寄稿学術誌査読

20 被引用数 (Scopus)

抄録

We have previously reported that a receptor-type adenylyl cyclase (CyaA) of Myxococcus xanthus undergoes an osmosensor mainly during spore germination (Y. Kimura et al., J. Bacteriol. 184:3578-3585, 2002). In the present study, we cloned another receptor-type adenylyl cyclase gene (cyaB) and characterized the function of the cyaB-encoded protein. Disruption of cyaB generates a mutant that showed growth retardation at high ionic (NaCl) or high nonionic (sucrose) osmolarity. When vegetative cells were stimulated with 0.15 M NaCl, the increases in intracellular cyclic AMP levels of cyaB mutant cells were lower than those of wild-type cells. Under nonionic osmostress, the cyaB mutant exhibited reduced spore germination; however, the germination rate of the cyaB mutant was significantly higher than that of the cyaA mutant.

本文言語英語
ページ(範囲)3593-3598
ページ数6
ジャーナルJournal of bacteriology
187
10
DOI
出版ステータス出版済み - 5月 2005
外部発表はい

!!!All Science Journal Classification (ASJC) codes

  • 微生物学
  • 分子生物学

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