An adolescent female having hepatocellular carcinoma associated with hepatitis B virus genotype H with a deletion mutation in the pre-S2 region

Utako Oba, Yuhki Koga, Takayuki Hoshina, Aiko Suminoe, Kenji Abe, Makoto Hayashida, Tomoaki Taguchi, Toshiro Hara

研究成果: ジャーナルへの寄稿記事

3 引用 (Scopus)

抄録

The genotypes of hepatitis B virus (HBV) have a distinct geographical distribution, with HBV genotype H being very rare in East Asia, including Japan. We herein report the case of a 12-year-old Japanese female with hepatocellular carcinoma (HCC) who exhibited HBV genotype H. Notably, the HBV isolated from the patient had a deletion mutation in the pre-S2 region. The genome of HBV genotype H in the patient with HCC has not been analyzed in detail. The deletion mutations in the pre-S2 region, which may play an important role in hepatocarcinogenesis in children, can also present in genotype H.

元の言語英語
ページ(範囲)302-304
ページ数3
ジャーナルJournal of Infection and Chemotherapy
21
発行部数4
DOI
出版物ステータス出版済み - 4 1 2015

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Sequence Deletion
Hepatitis B virus
Hepatocellular Carcinoma
Genotype
Far East
Japan
Genome

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Pharmacology (medical)
  • Infectious Diseases

これを引用

An adolescent female having hepatocellular carcinoma associated with hepatitis B virus genotype H with a deletion mutation in the pre-S2 region. / Oba, Utako; Koga, Yuhki; Hoshina, Takayuki; Suminoe, Aiko; Abe, Kenji; Hayashida, Makoto; Taguchi, Tomoaki; Hara, Toshiro.

:: Journal of Infection and Chemotherapy, 巻 21, 番号 4, 01.04.2015, p. 302-304.

研究成果: ジャーナルへの寄稿記事

Oba, Utako ; Koga, Yuhki ; Hoshina, Takayuki ; Suminoe, Aiko ; Abe, Kenji ; Hayashida, Makoto ; Taguchi, Tomoaki ; Hara, Toshiro. / An adolescent female having hepatocellular carcinoma associated with hepatitis B virus genotype H with a deletion mutation in the pre-S2 region. :: Journal of Infection and Chemotherapy. 2015 ; 巻 21, 番号 4. pp. 302-304.
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AU - Abe, Kenji

AU - Hayashida, Makoto

AU - Taguchi, Tomoaki

AU - Hara, Toshiro

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