An altered DNA sequence encompassing the ras gene of Harvey murine sarcoma virus.

S. Yasuda, M. Furuichi, E. Soeda

研究成果: ジャーナルへの寄稿記事

6 引用 (Scopus)

抄録

The DNA fragment encompassing the ras gene of Harvey murine sarcoma virus was sequenced and assigned the coding region of a transforming protein, p21, to the sequence. Examination of nucleotide sequence, taken together with the result of analysis of the ras mRNAs (1), has revealed that p21 is encoded from a continuous coding region starting with the 5' proximal initiation codon but not a processed protein. However, there were found several differences between the sequence published by Dhar et. al. (2) and ours, including 9 deletions, 7 substitutions and 2 insertions of nucleotides in the published sequence of 997 nucleotides in length. Among these, one of the substitutions occurring in the coding region resulted in amino acid replacement of glycine by alanine at position 122 of p21. The evidences are presented with some of actual gel autoradiographs.

元の言語英語
ページ(範囲)5583-5588
ページ数6
ジャーナルNucleic acids research
12
発行部数14
DOI
出版物ステータス出版済み - 7 25 1984
外部発表Yes

Fingerprint

Harvey murine sarcoma virus
ras Genes
Initiator Codon
Alanine
Glycine
Proteins
Nucleotides
Gels
Amino Acids
Messenger RNA
DNA

All Science Journal Classification (ASJC) codes

  • Genetics

これを引用

An altered DNA sequence encompassing the ras gene of Harvey murine sarcoma virus. / Yasuda, S.; Furuichi, M.; Soeda, E.

:: Nucleic acids research, 巻 12, 番号 14, 25.07.1984, p. 5583-5588.

研究成果: ジャーナルへの寄稿記事

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