An approximation model of myocardial crossbridge for weak coupling calculation of left ventricle model and circulation model

Akira Amano, Yasuhiro Takada, Jianyin Lu, Takao Shimayoshi, Tetsuya Matsuda

研究成果: Chapter in Book/Report/Conference proceedingConference contribution

5 被引用数 (Scopus)

抄録

It is necessary to use complicated myocardial cell model and heart model to evaluate the regional energy production and consumption which leads to the unrealistic computational time. In this research, a left ventricle (LV) simulation model was constructed which includes accurate myocardial cell model. In order to simulate the model in realistic time, we introduced an approximation model of the crossbridge model which can be calculated with weak coupling calculation. The LV model was combined with a circulation model to validate the proposed model by calculating the hemodynamics parameters and ventricular energetics indices. The ESPVR (End Systolic Pressure Volume Relation) showed linear relation, and also the PVA - ATP consumption relation showed linear relation which are widely known as the physiological characteristics of mammalian hearts. From these results, we can say that the model can be used as a model for physiological simulation experiments which are related to the ventricular energetics.

本文言語英語
ホスト出版物のタイトルProceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
出版社IEEE Computer Society
ページ957-960
ページ数4
ISBN(印刷版)9781424418152
DOI
出版ステータス出版済み - 2008
外部発表はい
イベント30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - Vancouver, BC, カナダ
継続期間: 8 20 20088 25 2008

出版物シリーズ

名前Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"

その他

その他30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
国/地域カナダ
CityVancouver, BC
Period8/20/088/25/08

All Science Journal Classification (ASJC) codes

  • コンピュータ ビジョンおよびパターン認識
  • 信号処理
  • 生体医工学
  • 健康情報学

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