Analyses of native disulfide bond formations in the early stage of the folding process in mutant lysozymes where the long-range interactions in the denatured state were modulated

Tomonori Mishima, Takatoshi Ohkuri, Taiji Imoto, Tadashi Ueda

研究成果: ジャーナルへの寄稿学術誌査読

2 被引用数 (Scopus)

抄録

In order to clarify whether modulation of long-range interactions in the denatured state affect native disulfide bond (SS bond) formations of hen egg white lysozyme (HEL) containing a pair of cysteine residues, we examined the extent of SS bond formation among 12 variants containing a pair of cysteines. The loss of clusters 5 and 6 in the denatured state affected the formation of Cys30-Cys115 and Cys6-Cys127 respectively.

本文言語英語
ページ(範囲)2072-2074
ページ数3
ジャーナルBioscience, Biotechnology and Biochemistry
71
8
DOI
出版ステータス出版済み - 2007

!!!All Science Journal Classification (ASJC) codes

  • バイオテクノロジー
  • 分析化学
  • 生化学
  • 応用微生物学とバイオテクノロジー
  • 分子生物学
  • 有機化学

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